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Oral immunization with purified\n            <jats:italic>H. pylori<\/jats:italic>\n            antigens protected mice from bacterial infection. This mouse model will allow the development of therapeutic agents and vaccines against\n            <jats:italic>H. pylori<\/jats:italic>\n            infection in humans.\n          <\/jats:p>","DOI":"10.1126\/science.7886456","type":"journal-article","created":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T18:19:42Z","timestamp":1161973182000},"page":"1655-1658","source":"Crossref","is-referenced-by-count":464,"title":["Development of a Mouse Model of\n            <i>Helicobacter pylori<\/i>\n            Infection that Mimics Human Disease"],"prefix":"10.1126","volume":"267","author":[{"given":"Marta","family":"Marchetti","sequence":"first","affiliation":[{"name":"Immunobiological Research Institute Siena (IRIS), Biocine SpA, Italy."}]},{"given":"Beatrice","family":"Aric\u00f2","sequence":"additional","affiliation":[{"name":"Immunobiological Research Institute Siena (IRIS), Biocine SpA, Italy."}]},{"given":"Daniela","family":"Burroni","sequence":"additional","affiliation":[{"name":"Immunobiological Research Institute Siena (IRIS), Biocine SpA, Italy."}]},{"given":"Natale","family":"Figura","sequence":"additional","affiliation":[{"name":"Istituto di Patologia Speciale Medica, University of Siena, Siena, Italy"}]},{"given":"Rino","family":"Rappuoli","sequence":"additional","affiliation":[{"name":"Immunobiological Research Institute Siena (IRIS), Biocine SpA, Italy."}]},{"given":"Paolo","family":"Ghiara","sequence":"additional","affiliation":[{"name":"Immunobiological Research Institute Siena (IRIS), Biocine SpA, Italy."}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.1994.03520010077036","volume":"272","year":"1994","unstructured":"JAMA-J AM MED ASSOC 272: 65 (1994).","journal-title":"JAMA-J AM MED ASSOC"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1139\/m90-041","volume":"36","year":"1990","unstructured":"CANTORNA, M.T., INABILITY OF HUMAN CLINICAL STRAINS OF HELICOBACTER-PYLORI TO COLONIZE THE ALIMENTARY-TRACT OF GERM-FREE RODENTS, CANADIAN JOURNAL OF MICROBIOLOGY 36: 237 (1990).","journal-title":"CANADIAN JOURNAL OF MICROBIOLOGY"},{"key":"e_1_2_1_3_1","first-page":"155","volume":"280","year":"1994","unstructured":"CHEN, M, INT J MED MICROBIOL 280: 155 (1994).","journal-title":"INT J MED MICROBIOL"},{"key":"e_1_2_1_4_1","first-page":"5791","volume":"90","year":"1993","unstructured":"COVACCI, A, MOLECULAR CHARACTERIZATION OF THE 128-KDA IMMUNODOMINANT ANTIGEN OF HELICOBACTER-PYLORI-ASSOCIATED WITH CYTOTOXICITY AND DUODENAL-ULCER, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90: 5791 (1993).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90477-7"},{"key":"e_1_2_1_6_1","first-page":"1644","volume":"92","year":"1995","unstructured":"DOUCE, G, MUTANTS OF ESCHERICHIA-COLI HEAT-LABILE TOXIN LACKING ADP-RIBOSYLTRANSFERASE ACTIVITY ACT AS NONTOXIC, MUCOSAL ADJUVANTS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92: 1644 (1995).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"9464","DOI":"10.1016\/S0021-9258(19)38872-6","volume":"265","year":"1990","unstructured":"Dunn, B. 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