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To address this, we proposed a biohybrid hand with multijointed fingers powered by multiple muscle tissue actuators (MuMuTAs), bundles of thin muscle tissues. The MuMuTA can provide linear actuation with high contractile force (~8 millinewtons) and high contractile length (~4 millimeters), which can be converted into the flexion of multijointed fingers by a cable-driven mechanism. We successfully powered the biohybrid hand achieving individual control of fingers and a variety of motions using different signaling controls. 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