{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T00:03:45Z","timestamp":1704845025279},"reference-count":1,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Aging Knowl. Environ."],"published-print":{"date-parts":[[2002,4,10]]},"abstract":"<jats:p>Defects in helicase enzymes result in a number of diseases that mimic aspects of growing old. New work shows that a helicase implicated in one of these conditions--xeroderma pigmentosum (XP)--apparently helps hormones activate genes in addition to its well-known ability to unwind DNA. The protein's newly discovered role in hormone signaling might underlie unexplained XP symptoms.<\/jats:p>","DOI":"10.1126\/sageke.2002.14.nf6","type":"journal-article","created":{"date-parts":[[2003,8,8]],"date-time":"2003-08-08T00:18:50Z","timestamp":1060301930000},"source":"Crossref","is-referenced-by-count":0,"title":["An Untwister's New Twist"],"prefix":"10.1126","volume":"2002","author":[{"given":"R. John","family":"Davenport","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_1_1_1","doi-asserted-by":"crossref","unstructured":"A. Keriel A. Stary A. Sarasin C. Rochette-Egly J.-M. Egly XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RAR\u03b1. Cell 109 125-135 (2002). [Abstract] [Full Text]","DOI":"10.1016\/S0092-8674(02)00692-X"}],"container-title":["Science of Aging Knowledge Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/full\/10.1126\/sageke.2002.14.nf6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T19:25:29Z","timestamp":1704828329000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sageke.2002.14.nf6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,4,10]]},"references-count":1,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2002,4,10]]}},"alternative-id":["10.1126\/sageke.2002.14.nf6"],"URL":"https:\/\/doi.org\/10.1126\/sageke.2002.14.nf6","relation":{},"ISSN":["1539-6150","1539-6150"],"issn-type":[{"value":"1539-6150","type":"print"},{"value":"1539-6150","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,4,10]]}}}