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Once that capacity is exhausted, a cycle of pathological inflammation ensues and leads to overt disease manifestations. Augmentation of stem cell-mediated repair systems may provide a novel means of treating or preventing many age-related illnesses.<\/jats:p>","DOI":"10.1126\/sageke.2003.45.re8","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T08:12:27Z","timestamp":1072167147000},"source":"Crossref","is-referenced-by-count":16,"title":["On the Memory of a Chronic Illness"],"prefix":"10.1126","volume":"2003","author":[{"given":"Pascal J.","family":"Goldschmidt-Clermont","sequence":"first","affiliation":[{"name":"Pascal J. Goldschmidt-Clermont is chair of the Department of Medicine and Eric D. Peterson is in the Division of Cardiology, Department of Medicine and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA.(P.J.G.-C.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Pascal J. Goldschmidt-Clermont is chair of the Department of Medicine and Eric D. Peterson is in the Division of Cardiology, Department of Medicine and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA.(P.J.G.-C.)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S0002-9343(02)01484-5","volume":"114","year":"2003","unstructured":"H. J. Cohen, T. Harris, C. F. Pieper, Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am. J. 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We also recognize the support of the Doris Duke Charitable Foundation (Clinical Interfaces Award to P.J.G.-C.) and the National Institute on Aging (NIA AG023073)."}],"container-title":["Science of Aging Knowledge Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/sageke.2003.45.re8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T18:01:13Z","timestamp":1704823273000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sageke.2003.45.re8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,12]]},"references-count":21,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2003,11,12]]}},"alternative-id":["10.1126\/sageke.2003.45.re8"],"URL":"https:\/\/doi.org\/10.1126\/sageke.2003.45.re8","relation":{},"ISSN":["1539-6150","1539-6150"],"issn-type":[{"value":"1539-6150","type":"print"},{"value":"1539-6150","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,11,12]]}}}