{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:01:36Z","timestamp":1791068496786,"version":"4.1.0"},"reference-count":44,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI063503"],"award-info":[{"award-number":["R01 AI063503"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R43AI138904"],"award-info":[{"award-number":["R43AI138904"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Adv."],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>A novel immunotherapy targeting the Mucorales unique CoH3 invasin is highly protective against murine mucormycosis.<\/jats:p>","DOI":"10.1126\/sciadv.aaw1327","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T23:15:35Z","timestamp":1560381335000},"source":"Crossref","is-referenced-by-count":88,"title":["Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis"],"prefix":"10.1126","volume":"5","author":[{"given":"Teclegiorgis","family":"Gebremariam","sequence":"first","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sondus","family":"Alkhazraji","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameh S. M.","family":"Soliman","sequence":"additional","affiliation":[{"name":"Sharjah Institute for Medical Research, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyou","family":"Gu","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heewon H.","family":"Jeon","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Zhang","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"College of Wildlife Resources, Northeast Forestry University, Harbin, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel W.","family":"French","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Stevens","sequence":"additional","affiliation":[{"name":"California Institute for Medical Research, San Jose, CA, USA."},{"name":"The Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7608-6021","authenticated-orcid":true,"suffix":"Jr.","given":"John E.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7278-3700","authenticated-orcid":true,"given":"Scott G.","family":"Filler","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Uppuluri","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3787-8530","authenticated-orcid":true,"given":"Ashraf S.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Los Angeles Biomedical Research Institute at Harbor\u2013University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA."},{"name":"Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.3.556-569.2005"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1128\/CMR.13.2.236","article-title":"Zygomycetes in human disease","volume":"13","author":"Ribes J. A.","year":"2000","unstructured":"J. A. Ribes, C. L. Vanover-Sams, D. J. Baker, Zygomycetes in human disease. Clin. Microbiol. Rev. 13, 236\u2013301 (2000).","journal-title":"Clin. Microbiol. Rev."},{"key":"e_1_3_2_4_2","unstructured":"A. M. Sugar Agents of mucormycosis and related species in Principles and Practice of Infectious Diseases G. L. Mandell J. E. Bennett R. Dolin Eds. (Elsevier Churchill Livingstone 2005) vol. 2 pp. 2973\u20132984."},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1128\/CMR.00056-10","article-title":"Mucormycosis caused by unusual mucormycetes, non-Rhizopus, -Mucor, and -Lichtheimia species","volume":"24","author":"Gomes M. Z. R.","year":"2011","unstructured":"M. Z. R. Gomes, R. E. Lewis, D. P. Kontoyiannis, Mucormycosis caused by unusual mucormycetes, non-Rhizopus, -Mucor, and -Lichtheimia species. Clin. Microbiol. Rev. 24, 411\u2013445 (2011).","journal-title":"Clin. Microbiol. Rev."},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1056\/NEJMoa1204781","article-title":"Necrotizing cutaneous mucormycosis after a tornado in Joplin, Missouri, in 2011","volume":"367","author":"Neblett Fanfair R.","year":"2012","unstructured":"R. Neblett Fanfair, K. Benedict, J. Bos, S. D. Bennett, Y.-C. Lo, T. Adebanjo, K. Etienne, E. Deak, G. Derado, W.-J. Shieh, C. Drew, S. Zaki, D. Sugerman, L. Gade, E. H. Thompson, D. A. Sutton, D. M. Engelthaler, J. M. Schupp, M. E. Brandt, J. R. Harris, S. R. Lockhart, G. Turabelidze, B. J. Park, Necrotizing cutaneous mucormycosis after a tornado in Joplin, Missouri, in 2011. N. Engl. J. Med. 367, 2214\u20132225 (2012).","journal-title":"N. Engl. J. Med."},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s12281-014-0205-y","article-title":"Combat-related invasive fungal wound infections","volume":"8","author":"Tribble D. R.","year":"2014","unstructured":"D. R. Tribble, C. J. Rodriguez, Combat-related invasive fungal wound infections. Curr. Fungal Infect. Rep. 8, 277\u2013286 (2014).","journal-title":"Curr. Fungal Infect. Rep."},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/mmy\/myu054","article-title":"Cutaneous mucormycosis and motor vehicle accidents: Findings from an Australian case series","volume":"52","author":"Ingram P. R.","year":"2014","unstructured":"P. R. Ingram, A. E. Suthananthan, R. Rajan, T. M. Pryce, K. Sieunarine, D. J. Gardam, C. H. Heath, Cutaneous mucormycosis and motor vehicle accidents: Findings from an Australian case series. Med. Mycol. 52, 819\u2013825 (2014).","journal-title":"Med. Mycol."},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1086\/313803","article-title":"Zygomycosis in the 1990s in a tertiary-care cancer center","volume":"30","author":"Kontoyiannis D. P.","year":"2000","unstructured":"D. P. Kontoyiannis, V. C. Wessel, G. P. Bodey, K. V. I. Rolston, Zygomycosis in the 1990s in a tertiary-care cancer center. Clin. Infect. Dis. 30, 851\u2013856 (2000).","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1086\/651263","article-title":"Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001\u20132006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database","volume":"50","author":"Kontoyiannis D. P.","year":"2010","unstructured":"D. P. Kontoyiannis, K. A. Marr, B. J. Park, B. D. Alexander, E. J. Anaissie, T. J. Walsh, J. Ito, D. R. Andes, J. W. Baddley, J. M. Brown, L. M. Brumble, A. G. Freifeld, S. Hadley, L. A. Herwaldt, C. A. Kauffman, K. Knapp, G. M. Lyon, V. A. Morrison, G. Papanicolaou, T. F. Patterson, T. M. Perl, M. G. Schuster, R. Walker, K. A. Wannemuehler, J. R. Wingard, T. M. Chiller, P. G. Pappas, Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001\u20132006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin. Infect. Dis. 50, 1091\u20131100 (2010).","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/00001432-200412000-00003","article-title":"Zygomycosis (mucormycosis): Emerging clinical importance and new treatments","volume":"17","author":"Greenberg R. N.","year":"2004","unstructured":"R. N. Greenberg, L. J. Scott, H. H. Vaughn, J. A. Ribes, Zygomycosis (mucormycosis): Emerging clinical importance and new treatments. Curr. Opin. Infect. Dis. 17, 517\u2013525 (2004).","journal-title":"Curr. Opin. Infect. Dis."},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.3201\/eid1509.090334","article-title":"Increasing incidence of zygomycosis (mucormycosis), France, 1997\u20132006","volume":"15","author":"Bitar D.","year":"2009","unstructured":"D. Bitar, D. Van Cauteren, F. Lanternier, E. Dannaoui, D. Che, F. Dromer, J.-C. Desenclos, O. Lortholary, Increasing incidence of zygomycosis (mucormycosis), France, 1997\u20132006. Emerg. Infect. Dis. 15, 1395\u20131401 (2009).","journal-title":"Emerg. Infect. Dis."},{"issue":"3","key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/myc.12243","article-title":"Mucormycosis in India: Unique features","volume":"57","author":"Chakrabarti A.","year":"2014","unstructured":"A. Chakrabarti, R. Singh, Mucormycosis in India: Unique features. Mycoses 57 (suppl. 3), 85\u201390 (2014).","journal-title":"Mycoses"},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s15010-018-1195-4","article-title":"Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: A case series","volume":"46","author":"El Zein S.","year":"2018","unstructured":"S. El Zein, J. El-Sheikh, A. Zakhem, D. Ibrahim, A. Bazarbachi, S. S. Kanj, Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: A case series. Infection 46, 811\u2013821 (2018).","journal-title":"Infection"},{"key":"e_1_3_2_15_2","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1128\/JCM.01744-09","article-title":"Species recognition and clinical relevance of the zygomycetous genus Lichtheimia (syn. Absidia Pro Parte, Mycocladus)","volume":"48","author":"Alastruey-Izquierdo A.","year":"2010","unstructured":"A. Alastruey-Izquierdo, K. Hoffmann, G. S. de Hoog, J. L. Rodriguez-Tudela, K. Voigt, E. Bibashi, G. Walther, Species recognition and clinical relevance of the zygomycetous genus Lichtheimia (syn. Absidia Pro Parte, Mycocladus). J. Clin. Microbiol. 48, 2154\u20132170 (2010).","journal-title":"J. Clin. Microbiol."},{"key":"e_1_3_2_16_2","doi-asserted-by":"crossref","first-page":"492","DOI":"10.3324\/haematol.2012.065110","article-title":"Diagnosis and treatment of mucormycosis in patients with hematological malignancies: Guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3)","volume":"98","author":"Skiada A.","year":"2013","unstructured":"A. Skiada, F. Lanternier, A. H. Groll, L. Pagano, S. Zimmerli, R. Herbrecht, O. Lortholary, G. L. Petrikkos, Diagnosis and treatment of mucormycosis in patients with hematological malignancies: Guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3). Haematologica 98, 492\u2013504 (2013).","journal-title":"Haematologica"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1469-0691.2009.02989.x","article-title":"Orbitomaxillary mucormycosis (zygomycosis) and the surgical approach to treatment: Perspectives from a maxillofacial surgeon","volume":"15","author":"Rapidis A. D.","year":"2009","unstructured":"A. D. Rapidis, Orbitomaxillary mucormycosis (zygomycosis) and the surgical approach to treatment: Perspectives from a maxillofacial surgeon. Clin. Microbiol. Infect. 15, 98\u2013102 (2009).","journal-title":"Clin. Microbiol. Infect."},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1128\/IAI.73.2.778-783.2005","article-title":"Rhizopus oryzae adheres to, is phagocytosed by, and damages endothelial cells in vitro","volume":"73","author":"Ibrahim A. S.","year":"2005","unstructured":"A. S. Ibrahim, B. Spellberg, V. Avanessian, Y. Fu, J. E. Edwards Jr., Rhizopus oryzae adheres to, is phagocytosed by, and damages endothelial cells in vitro. Infect. Immun. 73, 778\u2013783 (2005).","journal-title":"Infect. Immun."},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1172\/JCI71349","article-title":"CotH3 mediates fungal invasion of host cells during mucormycosis","volume":"124","author":"Gebremariam T.","year":"2014","unstructured":"T. Gebremariam, M. Liu, G. Luo, V. Bruno, Q. T. Phan, A. J. Waring, J. E. Edwards Jr., S. G. Filler, M. R. Yeaman, A. S. Ibrahim, CotH3 mediates fungal invasion of host cells during mucormycosis. J. Clin. Invest. 124, 237\u2013250 (2014).","journal-title":"J. Clin. Invest."},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1172\/JCI82744","article-title":"Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis","volume":"126","author":"Gebremariam T.","year":"2016","unstructured":"T. Gebremariam, L. Lin, M. Liu, D. P. Kontoyiannis, S. French, J. E. Edwards Jr., S. G. Filler, A. S. Ibrahim, Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J. Clin. Invest. 126, 2280\u20132294 (2016).","journal-title":"J. Clin. Invest."},{"key":"e_1_3_2_21_2","doi-asserted-by":"crossref","first-page":"12218","DOI":"10.1038\/ncomms12218","article-title":"An integrated genomic and transcriptomic survey of mucormycosis-causing fungi","volume":"7","author":"Chibucos M. C.","year":"2016","unstructured":"M. C. Chibucos, S. Soliman, T. Gebremariam, H. Lee, S. Daugherty, J. Orvis, A. C. Shetty, J. Crabtree, T. H. Hazen, K. A. Etienne, P. Kumari, T. D. O\u2019Connor, D. A. Rasko, S. G. Filler, C. M. Fraser, S. R. Lockhart, C. D. Skory, A. S. Ibrahim, V. M. Bruno, An integrated genomic and transcriptomic survey of mucormycosis-causing fungi. Nat. Commun. 7, 12218 (2016).","journal-title":"Nat. Commun."},{"key":"e_1_3_2_22_2","doi-asserted-by":"crossref","first-page":"3340","DOI":"10.1128\/AAC.00313-13","article-title":"Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis","volume":"57","author":"Luo G.","year":"2013","unstructured":"G. Luo, T. Gebremariam, H. Lee, S. W. French, N. P. Wiederhold, T. F. Patterson, S. G. Filler, A. S. Ibrahim, Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis. Antimicrob. Agents Chemother. 57, 3340\u20133347 (2013).","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_2_23_2","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1089\/ars.2009.2538","article-title":"Myeloperoxidase: Molecular mechanisms of action and their relevance to human health and disease","volume":"11","author":"van der Veen B. S.","year":"2009","unstructured":"B. S. van der Veen, M. P. J. de Winther, P. Heeringa, Myeloperoxidase: Molecular mechanisms of action and their relevance to human health and disease. Antioxid. Redox Signal. 11, 2899\u20132937 (2009).","journal-title":"Antioxid. Redox Signal."},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2194"},{"key":"e_1_3_2_25_2","doi-asserted-by":"crossref","first-page":"e48391","DOI":"10.1371\/journal.pone.0048391","article-title":"Comparison of the kinetics of maturation of phagosomes containing apoptotic cells and IgG-opsonized particles","volume":"7","author":"Viegas M. S.","year":"2012","unstructured":"M. S. Viegas, L. M. B. B. Estronca, O. V. Vieira, Comparison of the kinetics of maturation of phagosomes containing apoptotic cells and IgG-opsonized particles. PLOS ONE 7, e48391 (2012).","journal-title":"PLOS ONE"},{"key":"e_1_3_2_26_2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1128\/AAC.50.1.126-133.2006","article-title":"Posaconazole as salvage therapy for zygomycosis","volume":"50","author":"Greenberg R. N.","year":"2005","unstructured":"R. N. Greenberg, K. Mullane, J.-A.-H. van Burik, I. Raad, M. J. Abzug, G. Anstead, R. Herbrecht, A. Langston, K. A. Marr, G. Schiller, M. Schuster, J. R. Wingard, C. E. Gonzalez, S. G. Revankar, G. Corcoran, R. J. Kryscio, R. Hare, Posaconazole as salvage therapy for zygomycosis. Antimicrob. Agents Chemother. 50, 126\u2013133 (2005).","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_2_27_2","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1172\/JCI42164","article-title":"The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice","volume":"120","author":"Liu M.","year":"2010","unstructured":"M. Liu, B. Spellberg, Q. T. Phan, Y. Fu, A. S. Lee, J. E. Edwards Jr., S. G. Filler, A. S. Ibrahim, The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice. J. Clin. Invest. 120, 1914\u20131924 (2010).","journal-title":"J. Clin. Invest."},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2017-0167"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602615"},{"key":"e_1_3_2_30_2","doi-asserted-by":"crossref","first-page":"e5392","DOI":"10.1371\/journal.pone.0005392","article-title":"Protection by Anti-\u03b2-glucan antibodies is associated with restricted \u03b2-1,3 glucan binding specificity and inhibition of fungal growth and adherence","volume":"4","author":"Torosantucci A.","year":"2009","unstructured":"A. Torosantucci, P. Chiani, C. Bromuro, F. De Bernardis, A. S. Palma, Y. Liu, G. Mignogna, B. Maras, M. Colone, A. Stringaro, S. Zamboni, T. Feizi, A. Cassone, Protection by Anti-\u03b2-glucan antibodies is associated with restricted \u03b2-1,3 glucan binding specificity and inhibition of fungal growth and adherence. PLOS ONE 4, e5392 (2009).","journal-title":"PLOS ONE"},{"key":"e_1_3_2_31_2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/00002030-199904160-00005","article-title":"Antibody to capsular polysaccharide enhances the function of neutrophils from patients with AIDS against Cryptococcus neoformans","volume":"13","author":"Monari C.","year":"1999","unstructured":"C. Monari, A. Casadevall, C. Retini, F. Baldelli, F. Bistoni, A. Vecchiarelli, Antibody to capsular polysaccharide enhances the function of neutrophils from patients with AIDS against Cryptococcus neoformans. AIDS 13, 653\u2013660 (1999).","journal-title":"AIDS"},{"key":"e_1_3_2_32_2","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1128\/iai.38.3.1123-1129.1982","article-title":"Generation of chemotactic factors by Rhizopus oryzae in the presence and absence of serum: Relationship to hyphal damage mediated by human neutrophils and effects of hyperglycemia and ketoacidosis","volume":"38","author":"Chinn R. Y.","year":"1982","unstructured":"R. Y. Chinn, R. D. Diamond, Generation of chemotactic factors by Rhizopus oryzae in the presence and absence of serum: Relationship to hyphal damage mediated by human neutrophils and effects of hyperglycemia and ketoacidosis. Infect. Immun. 38, 1123\u20131129 (1982).","journal-title":"Infect. Immun."},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.12.001"},{"key":"e_1_3_2_34_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-59745-554-1_1","article-title":"Therapeutic Antibodies: Current state and future trends \u2013 Is a paradigm change coming soon?","volume":"525","author":"Dimitrov D. S.","year":"2009","unstructured":"D. S. Dimitrov, J. D. Marks, Therapeutic Antibodies: Current state and future trends \u2013 Is a paradigm change coming soon? Methods Mol. Biol. 525, 1\u201327 (2009).","journal-title":"Methods Mol. Biol."},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr375"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/jps.21152"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107470"},{"key":"e_1_3_2_38_2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1086\/591461","article-title":"Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis","volume":"198","author":"Ibrahim A. S.","year":"2008","unstructured":"A. S. Ibrahim, T. Gebremariam, M. Liu, G. Chamilos, D. Kontoyiannis, R. Mink, K. J. Kwon-Chung, Y. Fu, C. D. Skory, J. E. Edwards Jr., B. Spellberg, Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis. J. Infect. Dis. 198, 1083\u20131090 (2008).","journal-title":"J. Infect. Dis."},{"key":"e_1_3_2_39_2","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1128\/IAI.68.4.1997-2002.2000","article-title":"Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells","volume":"68","author":"Tsuchimori N.","year":"2000","unstructured":"N. Tsuchimori, L. L. Sharkey, W. A. Fonzi, S. W. French, J. E. Edwards Jr., S. G. Filler, Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells. Infect. Immun. 68, 1997\u20132002 (2000).","journal-title":"Infect. Immun."},{"key":"e_1_3_2_40_2","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1128\/AAC.49.2.721-727.2005","article-title":"Caspofungin inhibits Rhizopus oryzae 1,3-\u03b2-d-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis","volume":"49","author":"Ibrahim A. S.","year":"2005","unstructured":"A. S. Ibrahim, J. C. Bowman, V. Avanessian, K. Brown, B. Spellberg, J. E. Edwards Jr., C. M. Douglas, Caspofungin inhibits Rhizopus oryzae 1,3-\u03b2-d-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob. Agents Chemother. 49, 721\u2013727 (2005).","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32338"},{"key":"e_1_3_2_42_2","doi-asserted-by":"crossref","first-page":"e1000703","DOI":"10.1371\/journal.ppat.1000703","article-title":"Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice","volume":"5","author":"Lin L.","year":"2009","unstructured":"L. Lin, A. S. Ibrahim, X. Xu, J. M. Farber, V. Avanesian, B. Baquir, Y. Fu, S. W. French, J. E. Edwards Jr., B. Spellberg, Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLOS Pathog. 5, e1000703 (2009).","journal-title":"PLOS Pathog."},{"key":"e_1_3_2_43_2","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.3389\/fimmu.2017.01369","article-title":"Interaction of THP-1 monocytes with conidia and hyphae of different Curvularia strains","volume":"8","author":"T\u00f3th E. J.","year":"2017","unstructured":"E. J. T\u00f3th, \u00c9. Boros, A. Hoffmann, C. Szebenyi, M. Homa, G. Nagy, C. V\u00e1gv\u00f6lgyi, I. Nagy, T. Papp, Interaction of THP-1 monocytes with conidia and hyphae of different Curvularia strains. Front. Immunol. 8, 1369 (2017).","journal-title":"Front. Immunol."},{"key":"e_1_3_2_44_2","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/infdis\/172.4.1153","article-title":"A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT)","volume":"172","author":"Meshulam T.","year":"1995","unstructured":"T. Meshulam, S. M. Levitz, L. Christin, R. D. Diamond, A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT). J. Infect. Dis. 172, 1153\u20131156 (1995).","journal-title":"J. Infect. Dis."},{"key":"e_1_3_2_45_2","doi-asserted-by":"crossref","first-page":"e25909","DOI":"10.1371\/journal.pone.0025909","article-title":"Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis","volume":"6","author":"Luo G.","year":"2011","unstructured":"G. Luo, A. S. Ibrahim, S. W. French, J. E. Edwards Jr., Y. Fu, Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis. PLOS ONE 6, e25909 (2011).","journal-title":"PLOS ONE"}],"container-title":["Science Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/sciadv.aaw1327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T18:53:13Z","timestamp":1704826393000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sciadv.aaw1327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1126\/sciadv.aaw1327"],"URL":"https:\/\/doi.org\/10.1126\/sciadv.aaw1327","relation":{},"ISSN":["2375-2548"],"issn-type":[{"value":"2375-2548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]},"article-number":"eaaw1327"}}