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Viral whole genome sequencing and phylogeographic analyses further demonstrated that culling before virus arrival slowed viral spatial spread, but reactive culling accelerated spread, suggesting that culling-induced changes in bat dispersal promoted viral invasions. Our findings question the core assumptions of density-dependent transmission and localized viral maintenance that underlie culling bats as a rabies prevention strategy and provide an epidemiological and evolutionary framework to understand the outcomes of interventions in complex wildlife disease systems.<\/jats:p>","DOI":"10.1126\/sciadv.add7437","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T20:54:02Z","timestamp":1679518442000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":63,"title":["Effects of culling vampire bats on the spatial spread and spillover of rabies virus"],"prefix":"10.1126","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5975-6505","authenticated-orcid":true,"given":"Mafalda","family":"Viana","sequence":"first","affiliation":[{"name":"School of Biodiversity, One Health and Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University 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