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We used mathematical models to recover risk factors for infection and underlying probabilities of severe disease and death. We observed 19.0% [95% confidence interval (CI):17.1 to 21.1] of JEV antibodies. On average, 0.7% (95% CI: 0.2 to 2.0) of the susceptible population gets infected yearly, with pig proximity being the main human infection risk factor. Our traps captured 10 different mosquito species that have been linked with JEV transmission. We estimated that 1 in 1000 infections results in severe disease, 1 in 10,000 results in death, and 76% of severe cases are missed by surveillance.<\/jats:p>","DOI":"10.1126\/sciadv.adp1657","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T14:01:16Z","timestamp":1723212076000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":9,"title":["Informing an investment case for Japanese encephalitis vaccine introduction in Bangladesh"],"prefix":"10.1126","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9999-8402","authenticated-orcid":true,"given":"Mariana Perez","family":"Duque","sequence":"first","affiliation":[{"name":"Pathogen Dynamics Group, Department of Genetics, University of Cambridge, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1347-4446","authenticated-orcid":true,"given":"Abu 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