{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:38:39Z","timestamp":1792031919058,"version":"4.4.0"},"reference-count":56,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"30","content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Sci. Adv."],"published-print":{"date-parts":[[2024,7,26]]},"abstract":"<jats:p>Ultrathin flexible photodetectors can be conformably integrated with the human body, offering promising advancements for emerging skin-interfaced sensors. However, the susceptibility to degradation in ambient and particularly in aqueous environments hinders their practical application. Here, we report a 3.2-micrometer-thick water-resistant organic photodetector capable of reliably monitoring vital sign while submerged underwater. Embedding the organic photoactive layer in an adhesive elastomer matrix induces multidimensional hybrid phase separation, enabling high adhesiveness of the photoactive layer on both the top and bottom surfaces with maintained charge transport. This improves the water-immersion stability of the photoactive layer and ensures the robust sealing of interfaces within the device, notably suppressing fluid ingression in aqueous environments. Consequently, our fabricated ultrathin organic photodetector demonstrates stability in deionized water or cell nutrient media over extended periods, high detectivity, and resilience to cyclic mechanical deformation. We also showcase its potential for vital sign monitoring while submerged underwater.<\/jats:p>","DOI":"10.1126\/sciadv.adp2679","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T17:59:07Z","timestamp":1721843947000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":70,"title":["A water-resistant, ultrathin, conformable organic photodetector for vital sign monitoring"],"prefix":"10.1126","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1169-3868","authenticated-orcid":true,"given":"Baocai","family":"Du","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering and Information Systems, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."},{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0097-5628","authenticated-orcid":true,"given":"Sixing","family":"Xiong","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3586-0815","authenticated-orcid":true,"given":"Lulu","family":"Sun","sequence":"additional","affiliation":[{"name":"Thin-Film Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4516-3247","authenticated-orcid":true,"given":"Yusaku","family":"Tagawa","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Information Systems, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daishi","family":"Inoue","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7152-4408","authenticated-orcid":true,"given":"Daisuke","family":"Hashizume","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7206-6496","authenticated-orcid":true,"given":"Wenqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Information Systems, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."},{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqi","family":"Guo","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1546-8864","authenticated-orcid":true,"given":"Tomoyuki","family":"Yokota","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Information Systems, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."},{"name":"Institute of Engineering Innovation, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2637-8194","authenticated-orcid":true,"given":"Shuxu","family":"Wang","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5526-6100","authenticated-orcid":true,"given":"Yasuhiro","family":"Ishida","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3592-388X","authenticated-orcid":true,"given":"Sunghoon","family":"Lee","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."},{"name":"Thin-Film Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8015-5819","authenticated-orcid":true,"given":"Kenjiro","family":"Fukuda","sequence":"additional","affiliation":[{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."},{"name":"Thin-Film Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3051-1138","authenticated-orcid":true,"given":"Takao","family":"Someya","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Information Systems, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan."},{"name":"RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."},{"name":"Thin-Film Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-019-0167-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-016-0008"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nphoton.2015.177"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adf9861"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.7.071114"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/adpr.202000076"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201808138"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw7846"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba2624"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adh2694"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310811"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2024.01.002"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2745"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1206157"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1501856"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","unstructured":"Y. Kim C. Choi E.-C. Chen A. G. S. Daniel A. Masurkar T. H. Schwartz H. Ma I. Kymissis An ultra thin implantable system for cerebral blood volume monitoring using flexible OLED and OPD in 2015 IEEE International Electron Devices Meeting (IEDM) (IEEE 2015) pp. 29.6.1\u201329.6.4; https:\/\/doi.org\/10.1109\/IEDM.2015.7409796.","DOI":"10.1109\/IEDM.2015.7409796"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c05178"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202006006"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202200260"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2879"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20016-3"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41560-017-0001-3"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joule.2023.02.013"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7TA10722F"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsenergylett.9b00274"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-44878-z"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310248"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-023-01418-y"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/cm802530x"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw2543"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201904634"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0MH00483A"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.201501927"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201904205"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0347-y"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/cssc.201600999"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja106299g"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05579-z"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202106732"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04053-6"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202212219"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/admt.202300234"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ade2988"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.201200673"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.808451"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aah4496"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202203487"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.solmat.2016.06.044"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.2c08018"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135659"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.32.2.365"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.10300"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adh1504"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34968-1"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abj6565"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41928-022-00874-z"}],"container-title":["Science Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/sciadv.adp2679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T18:00:08Z","timestamp":1721844008000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adp2679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,26]]},"references-count":56,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2024,7,26]]}},"alternative-id":["10.1126\/sciadv.adp2679"],"URL":"https:\/\/doi.org\/10.1126\/sciadv.adp2679","relation":{},"ISSN":["2375-2548"],"issn-type":[{"value":"2375-2548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,26]]},"assertion":[{"value":"2024-03-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"eadp2679"}}