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Here, we propose a lensless imaging method with programmable Fresnel zone aperture (FZA), termed LIP. With a commercial liquid crystal display, we designed an integrated LIP module and demonstrated its capability of high-quality artifact-free reconstruction through dynamic modulation and offset-FZA parallel merging. Compared to static-modulation approaches, LIP achieves a 2.5\u00d7 resolution enhancement and a 3 decibels improvement in signal-to-noise ratio in \u201cstatic mode\u201d while maintaining an interaction frame rate of 15 frames per second in \u201cdynamic mode.\u201d Experimental results demonstrate LIP\u2019s potential as a miniaturized platform for versatile advanced imaging tasks like virtual reality and human-computer interaction.<\/jats:p>","DOI":"10.1126\/sciadv.adt3909","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T14:22:12Z","timestamp":1742566932000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":33,"title":["Lensless imaging with a programmable Fresnel zone aperture"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3274-9761","authenticated-orcid":true,"given":"Xu","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Electronic and Optical Engineering, Nanjing University of Science and Technology, No. 200 Xiaolingwei Street, Nanjing, Jiangsu Province 210094, China."},{"name":"Jiangsu Key Laboratory of Spectral Imaging &amp; 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