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We demonstrate that, by a proper functionalization of the polysiloxane-based scintillator, it is possible to target the effective detection of different kinds of ionizing radiation. Specifically, besides protons, we develop a device able to detect thermal neutrons, targeting its use during Boron Neutron Capture Therapy. This work demonstrates how organic indirect detectors can be considered a universal radiation detecting platform able to monitor in real time and in situ the dose absorbed by patients during cancer treatments under different kinds of radiation.<\/jats:p>","DOI":"10.1126\/sciadv.adt7633","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T17:59:57Z","timestamp":1745603997000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":6,"title":["A wearable tool for real-time dose monitoring during cancer radiation therapies"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6292-0118","authenticated-orcid":true,"given":"Ilaria","family":"Fratelli","sequence":"first","affiliation":[{"name":"Department of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6\/2, 40127 Bologna, Italy."},{"name":"INFN, Sezione di Bologna, Viale Berti Pichat 6\/2, 40127 Bologna, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6702-2867","authenticated-orcid":true,"given":"Sara M.","family":"Carturan","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy."},{"name":"INFN-Laboratori Nazionali di Legnaro, Viale dell\u2019Universit\u00e0 2, Legnaro, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-9261","authenticated-orcid":true,"given":"Francesco","family":"Tommasino","sequence":"additional","affiliation":[{"name":"Department of Physics, University of Trento, Via Sommarive 9, Povo, 38123 Trento, Italy."},{"name":"Trento Institute for Fundamental Physics and Applications, Via Sommarive 9, Povo, 38123 Trento, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0852-1770","authenticated-orcid":true,"given":"Laura","family":"Basiric\u00f2","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, University of Bologna, Viale Berti Pichat 6\/2, 40127 Bologna, Italy."},{"name":"INFN, Sezione di Bologna, Viale Berti Pichat 6\/2, 40127 Bologna, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Pino","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, University of Padova, Via Marzolo 8, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3901-9230","authenticated-orcid":true,"given":"Antonio","family":"Valletta","sequence":"additional","affiliation":[{"name":"INFN, Sezione di RomaTre, Via Della Vasca Navale 84, 00146 Roma, Italy."},{"name":"Institute for Microelectronics and Microsystems, IMM-CNR, Via Del Fosso Del Cavaliere, 100, 00133 Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2518-7134","authenticated-orcid":true,"given":"Marcello","family":"Campajola","sequence":"additional","affiliation":[{"name":"INFN-Sezione di Napoli-Complesso Univ. di Monte S. 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