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By coupling CO\n            <jats:sub>2<\/jats:sub>\n            hydrogenation to esterification, methyl formate (MF) can be prepared as a promising alternative platform chemical. Herein, a robust, heterogeneous single-metal-site catalyst was prepared and shown to achieve methanol hydrocarboxylation rates superior to nanoparticle catalysts (up to 18.3\u00a0\u00b1\u00a00.6 mmol\u00a0hour\n            <jats:sup>\u22121<\/jats:sup>\n            <jats:inline-formula>\n              <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                <mml:mrow>\n                  <mml:msubsup>\n                    <mml:mi mathvariant=\"bold\">g<\/mml:mi>\n                    <mml:mtext>cat<\/mml:mtext>\n                    <mml:mrow>\n                      <mml:mo mathvariant=\"bold-italic\">\u2212<\/mml:mo>\n                      <mml:mn mathvariant=\"bold\">1<\/mml:mn>\n                    <\/mml:mrow>\n                  <\/mml:msubsup>\n                <\/mml:mrow>\n              <\/mml:math>\n            <\/jats:inline-formula>\n            ) while maintaining very high selectivity to MF (\u226595%). Characterization reveals isolated, monodisperse Ru-nitrosyl complexes bound to three O-atoms of the zeolite framework, and the robust catalyst formed achieves a cumulative turnover number of more than 3500 over eight cycles. This work pushes the boundaries of supported single-site catalysts in CO\n            <jats:sub>2<\/jats:sub>\n            utilization.\n          <\/jats:p>","DOI":"10.1126\/sciadv.adu2857","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T17:58:56Z","timestamp":1744826336000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":8,"title":["Single-site ruthenium catalyst supported on zeolite for CO\n            <sub>2<\/sub>\n            hydrogenation to methyl formate"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3702-9467","authenticated-orcid":true,"given":"Roland C.","family":"Turnell-Ritson","sequence":"first","affiliation":[{"name":"Institute of Chemical Sciences and Engineering, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), 1015 Lausanne, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1877-6451","authenticated-orcid":true,"given":"Lindsey E. 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