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The reconstructed volume is then used to create a near-realistic placenta model. Four variations of arterial inlets are designed to simulate both normal and abnormal flow patterns. A scaled version of the model is printed in three dimensions. Magnetic resonance imaging\u2013based velocity measurements inside the printed model, which is perfused with a Newtonian fluid at two Reynolds numbers, revealed that the flow patterns are primarily influenced by the Reynolds number and the dilation of the arterial inlet. The spiralization of the arterial pathway had only a minimal impact.<\/jats:p>","DOI":"10.1126\/sciadv.adw9753","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T17:58:56Z","timestamp":1755885536000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":6,"title":["High-resolution MRI reveals uteroplacental flow dynamics in a 3D-printed human placental cotyledon model"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4777-8234","authenticated-orcid":true,"given":"Nirav","family":"Barapatre","sequence":"first","affiliation":[{"name":"Department of Anatomy II, LMU Munich, Munich 80336, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0941-7454","authenticated-orcid":true,"given":"David","family":"Frank","sequence":"additional","affiliation":[{"name":"MRI Flow Lab, University Rostock, Rostock 18059, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz Edler","family":"von Koch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Dritter Orden, Munich 80638, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3116-1918","authenticated-orcid":true,"given":"Sven","family":"Grundmann","sequence":"additional","affiliation":[{"name":"MRI Flow Lab, University Rostock, Rostock 18059, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3562-138X","authenticated-orcid":true,"given":"Hans-Georg","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Anatomy II, LMU Munich, Munich 80336, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0133-8348","authenticated-orcid":true,"given":"Martin","family":"Bruschewski","sequence":"additional","affiliation":[{"name":"MRI Flow Lab, University Rostock, Rostock 18059, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.29.Suppl_10.9"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2014.0066"},{"key":"e_1_3_1_4_2","doi-asserted-by":"crossref","unstructured":"R. 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