{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:07:52Z","timestamp":1789164472655,"version":"build-2803163510"},"reference-count":44,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"2","funder":[{"DOI":"10.13039\/100010819","name":"Stiftelsen Tornspiran","doi-asserted-by":"publisher","award":["999 2024-08-30"],"award-info":[{"award-number":["999 2024-08-30"]}],"id":[{"id":"10.13039\/100010819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012538","name":"Swedish Cancer Foundation","doi-asserted-by":"publisher","award":["22 2237 P"],"award-info":[{"award-number":["22 2237 P"]}],"id":[{"id":"10.13039\/100012538","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019180","name":"HORIZON EUROPE European Research Council","doi-asserted-by":"publisher","award":["ERC 101041484"],"award-info":[{"award-number":["ERC 101041484"]}],"id":[{"id":"10.13039\/100019180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","award":["22 2319 P"],"award-info":[{"award-number":["22 2319 P"]}],"id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Svenska S\u00e4llskapet f\u00f6r Medicinsk Forskning","doi-asserted-by":"publisher","award":["PG-22-0432-H-01"],"award-info":[{"award-number":["PG-22-0432-H-01"]}],"id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Svenska S\u00e4llskapet f\u00f6r Medicinsk Forskning","doi-asserted-by":"publisher","award":["CG-22 0009"],"award-info":[{"award-number":["CG-22 0009"]}],"id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2022-01708"],"award-info":[{"award-number":["2022-01708"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2021-00513"],"award-info":[{"award-number":["2021-00513"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2022-01719"],"award-info":[{"award-number":["2022-01719"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["2022.0021"],"award-info":[{"award-number":["2022.0021"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PolyBio Research Foundation","award":["Balvi B43"],"award-info":[{"award-number":["Balvi B43"]}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2018-02330"],"award-info":[{"award-number":["2018-02330"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2021-01141"],"award-info":[{"award-number":["2021-01141"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2021-04779"],"award-info":[{"award-number":["2021-04779"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2022-01313"],"award-info":[{"award-number":["2022-01313"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["2021.0136"],"award-info":[{"award-number":["2021.0136"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018713","name":"Center for Innovative Medicine","doi-asserted-by":"publisher","award":["UI-988204"],"award-info":[{"award-number":["UI-988204"]}],"id":[{"id":"10.13039\/501100018713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2020-06121"],"award-info":[{"award-number":["2020-06121"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wibergs Stiftelse","award":["M20-0190"],"award-info":[{"award-number":["M20-0190"]}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2019-00969"],"award-info":[{"award-number":["2019-00969"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PolyBio Research Foundation","award":["Balvi B43 and B90"],"award-info":[{"award-number":["Balvi B43 and B90"]}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2022-01816"],"award-info":[{"award-number":["2022-01816"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Swedish Research","award":["2021-03069"],"award-info":[{"award-number":["2021-03069"]}]},{"name":"Swedish Research","award":["2021-01039"],"award-info":[{"award-number":["2021-01039"]}]},{"name":"Magnus Bergvalls Foundation","award":["2023-587"],"award-info":[{"award-number":["2023-587"]}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2021-00284"],"award-info":[{"award-number":["2021-00284"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Sci. Adv."],"published-print":{"date-parts":[[2026,1,9]]},"abstract":"<jats:p>\n                    CXCR5\n                    <jats:sup>+<\/jats:sup>\n                    CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells emerged as key mediators of antiviral immunity in the context of chronic infection. However, their functional attributes and tissue distribution remain incompletely defined, especially in relation to antigen specificity. Here, we investigated the anatomical localization and antiviral properties of CXCR5\n                    <jats:sup>+<\/jats:sup>\n                    CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells across multiple sites throughout the human body, with an emphasis on oropharyngeal lymphoid tissues. Tonsils harbored the highest frequencies of CXCR5\n                    <jats:sup>+<\/jats:sup>\n                    CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells compared to other tissues, many of which expressed Granzyme K and concurrently displayed tissue residency features, as demonstrated by single cell profiling. Irrespective of clonal identity and virus specificity, CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells expressed CXCR5 more commonly in tonsils compared to vascular circulation. CXCR5 expression was particularly prominent among tonsil-localized CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells targeting Epstein-Barr virus (EBV) latent antigens and associated with a PD-1\n                    <jats:sup>+<\/jats:sup>\n                    resident stem-like phenotype. These data identify a CXCR5\n                    <jats:sup>+<\/jats:sup>\n                    tissue-resident memory CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cell subset in human tonsils with a potential role in immune surveillance of EBV.\n                  <\/jats:p>","DOI":"10.1126\/sciadv.ady8316","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T18:58:36Z","timestamp":1767812316000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":3,"title":["CXCR5 identifies stem-like resident memory CD8\u207a T cells enriched for latent EBV specificity in tonsils"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6949-4270","authenticated-orcid":true,"given":"Olga","family":"Rivera Ballesteros","sequence":"first","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9773-8607","authenticated-orcid":true,"given":"Lisa","family":"Rieble","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3490-4361","authenticated-orcid":true,"given":"Curtis","family":"Cai","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7649-0593","authenticated-orcid":true,"given":"Takuya","family":"Sekine","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Nils\u00e9n","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."},{"name":"ME Transplantation, Karolinska University Hospital Huddinge, Stockholm, Sweden."},{"name":"Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6161-3156","authenticated-orcid":true,"given":"Sarah","family":"Adamo","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."},{"name":"Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5331-5522","authenticated-orcid":true,"given":"Thomas R.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Constantz","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8852-1924","authenticated-orcid":true,"given":"Julia","family":"Niessl","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5781-4350","authenticated-orcid":true,"given":"Eoghann","family":"White","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YouBeen","family":"Ko","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8433-036X","authenticated-orcid":true,"given":"Tobias","family":"Kammann","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4154-9010","authenticated-orcid":true,"given":"Elli","family":"Mouchtaridi","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Gao","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."},{"name":"Institute of Precision Medicine, Hospital of Sun Yat-sen University, Zhongshan 2nd Road, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3136-9284","authenticated-orcid":true,"given":"Akhirunnesa","family":"Mily","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5468-276X","authenticated-orcid":true,"given":"Elisa J. M.","family":"Raineri","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5568-8880","authenticated-orcid":true,"given":"Christopher","family":"Stamper","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3042-8206","authenticated-orcid":true,"given":"Anne","family":"Marchalot","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4009-473X","authenticated-orcid":true,"given":"Nicole","family":"Wild","sequence":"additional","affiliation":[{"name":"Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5932-6425","authenticated-orcid":true,"given":"Demi","family":"Brownlie","sequence":"additional","affiliation":[{"name":"Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4703-0413","authenticated-orcid":true,"given":"Sian","family":"Llewellyn-Lacey","sequence":"additional","affiliation":[{"name":"Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7730-7700","authenticated-orcid":true,"given":"Chris","family":"Tibbitt","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Micha\u00eblsson","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3186-4752","authenticated-orcid":true,"given":"Nicole","family":"Marquardt","sequence":"additional","affiliation":[{"name":"Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1119-0976","authenticated-orcid":true,"given":"Jenny","family":"Mj\u00f6sberg","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7727-8113","authenticated-orcid":true,"given":"Carl","family":"Jorns","sequence":"additional","affiliation":[{"name":"ME Transplantation, Karolinska University Hospital Huddinge, Stockholm, Sweden."},{"name":"Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6275-0750","authenticated-orcid":true,"given":"Johan K.","family":"Sandberg","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Driving","sequence":"additional","affiliation":[{"name":"Capio \u00d6ron N\u00e4sa Hals Globen\/Odenplan, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9416-2737","authenticated-orcid":true,"given":"David A.","family":"Price","sequence":"additional","affiliation":[{"name":"Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, UK."},{"name":"Systems Immunity Research Institute, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-1719","authenticated-orcid":true,"given":"Marcus","family":"Buggert","sequence":"additional","affiliation":[{"name":"Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01538-6"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10851"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aas9673"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-019-0464-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.12.012"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature19317"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature19330"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.622343"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aax4077"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.11.075"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12446-5"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200636746"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02287"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2018.10.002"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80622-6"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1301629"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20112401"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007110"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032414-112326"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02158-12"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.4.2019"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abk0894"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adq4881"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adn2362"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1426418"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abd5778"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.11.019"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2017.0208"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200636136"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1100898108"},{"key":"e_1_3_2_32_2","first-page":"103","article-title":"Immunoglobulin-containing cells in human tonsils as demonstrated by immunohistochemistry","volume":"28","author":"Curran R. C.","year":"1977","unstructured":"R. C. Curran, E. L. Jones, Immunoglobulin-containing cells in human tonsils as demonstrated by immunohistochemistry. Clin. Exp. Immunol. 28, 103\u2013115 (1977).","journal-title":"Clin. Exp. Immunol."},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.04.011"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aar4526"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1917298117"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.912038"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.173489"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2024.01.006"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005799"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.10.026"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells11172649"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007748"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1059133"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.113250"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20051357"}],"container-title":["Science Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/sciadv.ady8316","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T18:59:11Z","timestamp":1767812351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sciadv.ady8316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,9]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,1,9]]}},"alternative-id":["10.1126\/sciadv.ady8316"],"URL":"https:\/\/doi.org\/10.1126\/sciadv.ady8316","relation":{},"ISSN":["2375-2548"],"issn-type":[{"value":"2375-2548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,9]]},"assertion":[{"value":"2025-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"eady8316"}}