{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:58:43Z","timestamp":1793141923270,"version":"4.5.0"},"reference-count":97,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"51","funder":[{"DOI":"10.13039\/100007847","name":"Natural Science Foundation of Jilin Province","doi-asserted-by":"publisher","award":["20230101047JC, YDZJ202201ZYTS338"],"award-info":[{"award-number":["20230101047JC, YDZJ202201ZYTS338"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22193012, 22201033, 22371037, 22471034"],"award-info":[{"award-number":["22193012, 22201033, 22371037, 22471034"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key R & D Program of China","doi-asserted-by":"crossref","award":["2024YFA1509704"],"award-info":[{"award-number":["2024YFA1509704"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Sci. Adv."],"published-print":{"date-parts":[[2025,12,19]]},"abstract":"<jats:p>\n                    While radical difunctionalization offers substantial potential for molecular diversification, existing methodologies predominantly focus on styrenes and activated alkenes, leaving fundamental light olefins (e.g., ethylene and propylene) largely unexplored. Moreover, achieving stereoselective transformations of light olefins remains a formidable challenge. Here, we present a visible-light\u2013mediated photoredox-catalyzed chemo-divergent and regioselective radical difluoromethylation\/polyfluoroarylsulfonylation and difluoromethylation\/polyfluoroarylation of structurally diverse alkenes through switchable sulfur dioxide reintegration. The method demonstrates broad applicability across styrenes, unactivated alkenes, and gaseous ethylene\/propylene substrates. The photocatalyst functions as a switch, and Sodium difluoromethanesulfinate (CF\n                    <jats:sub>2<\/jats:sub>\n                    HSO\n                    <jats:sub>2<\/jats:sub>\n                    Na) acts as a bifunctional reagent, enabling controllable divergence radical conversion via radical-polar crossover pathways. Notably, chiral alcohol\u2013derived polyfluoroarenes efficiently induce stereoselectivity control in the coupling of alkyl radicals with sulfur dioxide via dynamic kinetic resolution. Density functional theory calculations indicate noncovalent interaction between alkyl\/aryl groups and polyfluorocarbons plays critical roles for the ultralong-distance (&gt;9 atoms) stereochemical induction. The key to achieving chemo-divergent and stereocontrolled transformations lies in the precise sorting of a dynamic intermediate pool containing alkyl radicals, sulfonyl radicals, and anions.\n                  <\/jats:p>","DOI":"10.1126\/sciadv.aeb0206","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T18:58:22Z","timestamp":1766170702000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":19,"title":["Photoredox-controlled chemo-divergent, regio-, and stereoselective difunctionalization of olefins via switchable SO\n                    <sub>2<\/sub>\n                    reintegration"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0022-0991","authenticated-orcid":true,"given":"Jiuli","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1213-5717","authenticated-orcid":true,"given":"Lihan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4307-8943","authenticated-orcid":true,"given":"Zhiguang","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0060-9860","authenticated-orcid":true,"given":"Yunliang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."},{"name":"School of Environment, Northeast Normal University, Changchun 130117, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0260-9436","authenticated-orcid":true,"given":"Lefeng","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8724-2664","authenticated-orcid":true,"given":"Jiaqiong","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."},{"name":"School of Environment, Northeast Normal University, Changchun 130117, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0201-6279","authenticated-orcid":true,"given":"Guangfan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3136-841X","authenticated-orcid":true,"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Northeast Normal University, Changchun 130024, China."},{"name":"State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","unstructured":"\u201cEthylene industry installed capacity and capital expenditure (CapEx) forecast by region and countries including details of all active plants planned and announced projects 2023-2027\u201d (GlobalData 2023); 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