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A second injection of azide-modified Gd-DOTA enables rapid copper-free click conjugation on the nanofibrillar scaffold, yielding a nearly fourfold increase in longitudinal relaxivity. MRI demonstrated strong\n                    <jats:italic toggle=\"yes\">T<\/jats:italic>\n                    <jats:sub>1<\/jats:sub>\n                    -weighted signal enhancement and high tumor-to-liver contrast in Hepa1-6 tumor-bearing mice. 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