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However, existing fluidic controllers in soft robots face scalability limitations, restricting their ability to handle growing degrees of freedom across sizes while preserving compliance. Here, we present a scalable fluidic control architecture that integrates high-radix demultiplexing with time multiplexing to achieve a high input-to-output ratio and reprogrammable actuation. We incorporate a design method based on dimensionless parameters to preserve comparable valve opening and closing pressure thresholds across different physical scales, thereby maintaining consistent addressing behavior of the demultiplexer after geometric scaling. In addition, structural stretchability enables seamless integration into soft bodies, maintaining reliable control under dynamic deformation without compromising compliance. This hybrid demultiplexer\/multiplexer fluidic circuit overcomes key limitations, offering functional scalability, geometric scalability, and physical integrability in a single architecture. Our approach enables autonomous, adaptable soft robots capable of complex, multifunctional motions, functioning as self-contained systems.<\/jats:p>","DOI":"10.1126\/sciadv.aed4468","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T18:06:59Z","timestamp":1791569219000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Scalable design of fluidic DEMUX\/MUX"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0840-7425","authenticated-orcid":true,"given":"Hwayeong","family":"Jeong","sequence":"first","affiliation":[{"name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), Lausanne, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3869-213X","authenticated-orcid":true,"given":"Jamie","family":"Paik","sequence":"additional","affiliation":[{"name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), Lausanne, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1825-6325","authenticated-orcid":true,"given":"Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Korea Advanced Institute of Science Technology (KAIST), Daejeon, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05058"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","unstructured":"Q. 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