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Adv."],"published-print":{"date-parts":[[2026,7,24]]},"abstract":"<jats:p>\n                    A central challenge in engineered living materials (ELMs) is the seamless integration of macroscopic structural assembly with sustained cellular viability and programmable function. Here, we report a fungal-based living material that addresses this challenge by preserving the metabolic activity of\n                    <jats:italic toggle=\"yes\">Cordyceps militaris<\/jats:italic>\n                    mycelia within macroscale, cohesive films fabricated via a low-energy process. These living textiles retain the capacity for environmental response, demonstrated by nutrient-induced aerial hyphal growth that enables surface renewal. The native mycelial architecture further allows for volumetric integration of engineered microbial partners, exemplified by coculture with pigment-producing\n                    <jats:italic toggle=\"yes\">Saccharomyces cerevisiae<\/jats:italic>\n                    for in situ patterning and melanized\n                    <jats:italic toggle=\"yes\">Aspergillus niger<\/jats:italic>\n                    for built-in ultraviolet shielding. This modular design decouples bulk structural fabrication from genetic functionalization, offering a plug-and-play platform for synthetic biology. Environmental assessments confirm near-complete morphological degradation within 41 days. Our work establishes a scalable and sustainable chassis for functional ELMs, bridging a critical gap between structural integrity and biological programmability.\n                  <\/jats:p>","DOI":"10.1126\/sciadv.aed6937","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:58:33Z","timestamp":1784915913000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":1,"title":["A programmable fungal platform for engineered living textiles"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4346-2531","authenticated-orcid":true,"given":"Ke","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, 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