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Adv."],"published-print":{"date-parts":[[2026,7,31]]},"abstract":"<jats:p>\n                    The efficient separation of monovalent and divalent ions remains a core challenge in desalination and ion resource recovery. Here, we propose an electrochemical confinement strategy to spatially organize EDTA into aligned arrays within the one-dimensional transport channels of TFP-Tag membrane with a pore size of 1.1 nm. This structure establishes a biomimetic, gradient-functionalized conical nanochannel. The negatively charged upper channel regions capture and block divalent ions, while the lower regions with their larger pore size and an anion-affinitive local environment facilitate monovalent ion transport, thereby achieving highly selective monovalent\/divalent ion separation. The membrane exhibits outstanding monovalent\/divalent ion separation performance in multi-ion mixed solutions, with Na\n                    <jats:sup>+<\/jats:sup>\n                    flux reaching 10.6 mmol m\n                    <jats:sup>\u22122<\/jats:sup>\n                    \u00a0hour\n                    <jats:sup>\u22121<\/jats:sup>\n                    and the selectivity of Na\n                    <jats:sup>+<\/jats:sup>\n                    \/Mg\n                    <jats:sup>2+<\/jats:sup>\n                    exceeding 500. This breakthrough separation behavior is attributed to an induced transport lag effect arising from the synergy between the COF structure and the chelation-assisted retardation of divalent ions by EDTA. This study establishes a theoretical framework for the rational design of ion-separation membranes exhibiting simultaneous high-selectivity and high-flux performance.\n                  <\/jats:p>","DOI":"10.1126\/sciadv.aee3640","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:58:34Z","timestamp":1785520714000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Electrochemically tailored ion-trapping nanoarchitectures in COF membranes for selective monovalent\/divalent ion sieving"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3702-3206","authenticated-orcid":true,"given":"Jing","family":"Wang","sequence":"first","affiliation":[{"name":"Hubei Key Laboratory of Multi\u2013media Pollution Cooperative Control in Yangtze Basin, School of Environmental Science &amp; Engineering, Huazhong University of Science and Technology (HUST), 1037 Luoyu 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