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Adv."],"published-print":{"date-parts":[[2026,9,18]]},"abstract":"<jats:p>\n                    Protein polymers conduct electricity due to the delocalization of \u03c0 electrons along the conjugated main chains, but their photoconductivity often shows unidirectional tunability. We report a protein polymer with bidirectional optoelectronic conductivity because of reversible light intensity\u2013dependent secondary structural transformation. The protein device shows a positive photocurrent under high light intensity (2.22 to 3.18 \u03bcW\u00b7\u03bcm\n                    <jats:sup>\u22122<\/jats:sup>\n                    and the wavelength of 405-nanometer illumination) illumination and a negative photocurrent under low light intensity (0.32 to 1.91 \u03bcW\u00b7\u03bcm\n                    <jats:sup>\u22122<\/jats:sup>\n                    ). Under low light intensity light, the helix structures untwist into a low-conductivity \u03b2-turn because only partial hydrogen bonds are damaged by insufficient low-energy excitons and Joule heat, whereas high-intensity light drives a transition to a high-conductivity \u03b2 sheet because most hydrogen bonds are destructed by high-energy excitons and sufficient Joule heat. The tunable low-conductivity state arises from an increase in \u03b2-turn content coupled with a decrease in \u03b2 sheet content, while the inverse transition enables the high-conductivity state. This bidirectional conductivity enables the fibroin-based device to perform in-sensor computing for real-time perception of multiple object motions.\n                  <\/jats:p>","DOI":"10.1126\/sciadv.aee6038","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:04:04Z","timestamp":1789754644000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Bidirectional optoelectronic switching in protein by photoinduced phase transition"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9827-2001","authenticated-orcid":true,"given":"Guangdong","family":"Zhou","sequence":"first","affiliation":[{"name":"College of Artificial Intelligence, Chongqing Key Laboratory of Brain-Inspired Computing and Intelligent Chips, Key Laboratory of Luminescence Analysis and Molecular Sensors (Ministry of Education), Southwest University, Chongqing, China."},{"name":"Department of Applied Physics, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuxia","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Artificial Intelligence, Chongqing Key Laboratory of Brain-Inspired Computing and Intelligent Chips, Key Laboratory of Luminescence Analysis and Molecular Sensors (Ministry of Education), Southwest University, Chongqing, China."},{"name":"Frontier Institute of Science and Technology, Xi\u2019an Jiaotong University, Shanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuesen","family":"Xie","sequence":"additional","affiliation":[{"name":"College of Artificial Intelligence, Chongqing Key Laboratory of Brain-Inspired Computing and Intelligent Chips, Key Laboratory of Luminescence Analysis and Molecular Sensors (Ministry of Education), Southwest University, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-007X","authenticated-orcid":true,"given":"Ye","family":"Zhou","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study, Shenzhen University, Shenzhen, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5840-509X","authenticated-orcid":true,"given":"Bai","family":"Sun","sequence":"additional","affiliation":[{"name":"Frontier Institute of Science and Technology, Xi\u2019an Jiaotong University, Shanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8943-0861","authenticated-orcid":true,"given":"Yang","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Applied Physics, The Hong Kong Polytechnic University, Kowloon, Hong Kong, 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