{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:21:30Z","timestamp":1790000490395,"version":"4.0.1"},"reference-count":21,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5643","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2003,10,10]]},"abstract":"<jats:p>\n            Neuronal axons connect to multiple target cells through the formation of collateral branches, but the mechanisms that regulate this process are largely unknown. We show that BAM-2, a neurexin-related transmembrane protein, is required for development of VC motoneuron branches in the worm\n            <jats:italic>Caenorhabditis elegans<\/jats:italic>\n            . Expression analysis and ectopic expression experiments suggest that BAM-2 functions as a branch termination cue and reveal a mechanism for selective control of branches that sprout off a primary axon.\n          <\/jats:p>","DOI":"10.1126\/science.1089163","type":"journal-article","created":{"date-parts":[[2003,10,10]],"date-time":"2003-10-10T09:37:46Z","timestamp":1065778666000},"page":"293-296","source":"Crossref","is-referenced-by-count":32,"title":["A Neurexin-Related Protein, BAM-2, Terminates Axonal Branches in\n            <i>C. elegans<\/i>"],"prefix":"10.1126","volume":"302","author":[{"given":"Antonio","family":"Colavita","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Tessier-Lavigne","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(00)01646-5"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.18.031802.150501"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/378192a0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80588-7"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-21-08548.2001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00713-4"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-10-06975.1995"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80527-9"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(90)90195-L"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.117.3.1071"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.19-01-00072.1999"},{"key":"e_1_3_2_13_2","unstructured":"A. Colavita M. Tessier-Lavigne data not shown."},{"key":"e_1_3_2_14_2","unstructured":"See supporting data on Science Online."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1621094"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9525(97)01324-3"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80877-6"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn1074"},{"key":"e_1_3_2_19_2","unstructured":"E. Peles personal communication."},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-133X(02)00055-8"},{"key":"e_1_3_2_21_2","unstructured":"P. Olsen V. Ambros personal communication."},{"key":"e_1_3_2_22_2","unstructured":"We thank C. Bargmann C. Chang Z. Chen and K. Shen for helpful discussions; C. Chang and Z. Chen for comments on the manuscript; Y. Kohara for cDNA clones; and the labs of V. Ambros C. Bargmann M. Driscoll A. Fire Y. Jin and P. Sternberg for constructs and strains. Supported by a grant from the Howard Hughes Medical Institute (HHMI) (M.T.-L.) and by a Jane Coffin Childs Memorial Fund fellowship (A.C.)."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1089163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T02:54:26Z","timestamp":1704855266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1089163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10,10]]},"references-count":21,"journal-issue":{"issue":"5643","published-print":{"date-parts":[[2003,10,10]]}},"alternative-id":["10.1126\/science.1089163"],"URL":"https:\/\/doi.org\/10.1126\/science.1089163","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10,10]]}}}