{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:12:21Z","timestamp":1779293541656,"version":"3.51.4"},"reference-count":10,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5644","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2003,10,17]]},"DOI":"10.1126\/science.1091258","type":"journal-article","created":{"date-parts":[[2003,10,16]],"date-time":"2003-10-16T21:09:09Z","timestamp":1066338549000},"page":"400-401","source":"Crossref","is-referenced-by-count":101,"title":["Gene Therapy--New Challenges Ahead"],"prefix":"10.1126","volume":"302","author":[{"given":"David A.","family":"Williams","sequence":"first","affiliation":[{"name":"D. A. Williams is in the Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Baum","sequence":"additional","affiliation":[{"name":"C. Baum is in the Department of Hematology and Oncology, Hannover Medical School, Hannover, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012616"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1070104"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1088547"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-07-2314"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-0016(03)00212-0"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00864-4"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083413"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068893"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-02-0407"},{"key":"e_1_3_1_11_2","unstructured":"Supported by the Deutsche Forschungsgemeinschaft (KFO 110) and European Union (QLRT-2001-00427 and QLK3-2001-01265) (C.B.) and NIH (HL53586) (D.A.W.)."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1091258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T03:00:33Z","timestamp":1704855633000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1091258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10,17]]},"references-count":10,"journal-issue":{"issue":"5644","published-print":{"date-parts":[[2003,10,17]]}},"alternative-id":["10.1126\/science.1091258"],"URL":"https:\/\/doi.org\/10.1126\/science.1091258","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10,17]]}}}