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Moreover,\n            <jats:italic>S-<\/jats:italic>\n            nitrosylation inhibits parkin's ubiquitin E3 ligase activity and its protective function. The inhibition of parkin's ubiquitin E3 ligase activity by\n            <jats:italic>S-<\/jats:italic>\n            nitrosylation could contribute to the degenerative process in these disorders by impairing the ubiquitination of parkin substrates.\n          <\/jats:p>","DOI":"10.1126\/science.1093891","type":"journal-article","created":{"date-parts":[[2004,4,27]],"date-time":"2004-04-27T00:43:22Z","timestamp":1083026602000},"page":"1328-1331","source":"Crossref","is-referenced-by-count":710,"title":["<i>S<\/i>\n            -Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function"],"prefix":"10.1126","volume":"304","author":[{"given":"Kenny K. K.","family":"Chung","sequence":"first","affiliation":[{"name":"Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bobby","family":"Thomas","sequence":"additional","affiliation":[{"name":"Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA."},{"name":"Department of Pathology, Johns Hopkins 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