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We found that the\n            <jats:italic>Leishmania<\/jats:italic>\n            RNA import complex (RIC) could enter human cells by a caveolin-1\u2013dependent pathway, where it induced import of endogenous cytosolic tRNAs, including tRNA\n            <jats:sup>Lys<\/jats:sup>\n            , and restored mitochondrial function in a cybrid harboring a mutant mt tRNA\n            <jats:sup>Lys<\/jats:sup>\n            (\n            <jats:italic>MT-TK<\/jats:italic>\n            ) gene. The use of protein complexes to modulate mitochondrial function may help in the management of such genetic disorders.\n          <\/jats:p>","DOI":"10.1126\/science.1129754","type":"journal-article","created":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T20:53:14Z","timestamp":1161291194000},"page":"471-474","source":"Crossref","is-referenced-by-count":94,"title":["Functional Delivery of a Cytosolic tRNA into Mutant Mitochondria of Human Cells"],"prefix":"10.1126","volume":"314","author":[{"given":"Bidesh","family":"Mahata","sequence":"first","affiliation":[{"name":"Genetic Engineering, Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Calcutta 700032, India."},{"name":"Molecular Endocrinology, Indian Institute of Chemical Biology, 4 Raja S. C. 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