{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:50:24Z","timestamp":1791226224259,"version":"4.1.0"},"reference-count":17,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5869","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2008,3,14]]},"abstract":"<jats:p>\n                    Edible fruits, such as that of the tomato plant and other vegetable crops, are markedly diverse in shape and size.\n                    <jats:italic>SUN<\/jats:italic>\n                    , one of the major genes controlling the elongated fruit shape of tomato, was positionally cloned and found to encode a member of the IQ67 domain\u2013containing family. We show that the locus arose as a result of an unusual 24.7-kilobase gene duplication event mediated by the long terminal repeat retrotransposon\n                    <jats:italic>Rider<\/jats:italic>\n                    . This event resulted in a new genomic context that increased\n                    <jats:italic>SUN<\/jats:italic>\n                    expression relative to that of the ancestral copy, culminating in an elongated fruit shape. Our discovery demonstrates that retrotransposons may be a major driving force in genome evolution and gene duplication, resulting in phenotypic change in plants.\n                  <\/jats:p>","DOI":"10.1126\/science.1153040","type":"journal-article","created":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T16:49:28Z","timestamp":1205426968000},"page":"1527-1530","source":"Crossref","is-referenced-by-count":564,"title":["A Retrotransposon-Mediated Gene Duplication Underlies Morphological Variation of Tomato Fruit"],"prefix":"10.1126","volume":"319","author":[{"given":"Han","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Horticulture and Crop Science, Ohio State University\/Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA."},{"name":"Department of Horticulture, Michigan State University, East Lansing, MI 48824, USA."},{"name":"College of Wooster, Wooster, OH 44691, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science, Ohio State University\/Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA."},{"name":"Department of Horticulture, Michigan State University, East Lansing, MI 48824, USA."},{"name":"College of Wooster, Wooster, OH 44691, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Schaffner","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science, Ohio State University\/Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA."},{"name":"Department of Horticulture, Michigan State University, East Lansing, MI 48824, USA."},{"name":"College of Wooster, Wooster, OH 44691, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Stockinger","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science, Ohio State University\/Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA."},{"name":"Department of Horticulture, Michigan State University, East Lansing, MI 48824, USA."},{"name":"College of Wooster, Wooster, OH 44691, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"van der Knaap","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science, Ohio State University\/Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA."},{"name":"Department of Horticulture, Michigan State University, East Lansing, MI 48824, USA."},{"name":"College of Wooster, Wooster, OH 44691, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.cell.2006.12.006","volume":"127","year":"2006","unstructured":"J. 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Mackey and P. Springer for comments. This work was funded in part by NSF: DBI 0227541 and DBI 0400811 (to E.v.d.K.); DBI 0110124 (to E.J.S.). Accession numbers of deposited sequences: EF094939 EF094940 EF094941 and EU491503."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1153040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T03:55:54Z","timestamp":1704858954000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1153040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,14]]},"references-count":17,"journal-issue":{"issue":"5869","published-print":{"date-parts":[[2008,3,14]]}},"alternative-id":["10.1126\/science.1153040"],"URL":"https:\/\/doi.org\/10.1126\/science.1153040","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1104427.565000","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1104427.560454","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,14]]}}}