{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:21:33Z","timestamp":1791825693522,"version":"4.3.4"},"reference-count":28,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5990","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2010,7,23]]},"abstract":"<jats:title>Heme Communication Revealed by Asymmetry<\/jats:title>\n                  <jats:p>\n                    An electronic bus bar is an electrical conductor that connects several circuits.\n                    <jats:bold>\n                      \u015awierczek\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"451\" related-article-type=\"in-this-issue\" vol=\"329\" xlink:href=\"10.1126\/science.1190899\">451<\/jats:related-article>\n                    ) now find that a similar strategy is used by the protein cytochrome bc\n                    <jats:sub>1<\/jats:sub>\n                    that plays a central role in cellular respiration and photosynthesis. Protein engineering was used to break the symmetry of a cytochrome bc\n                    <jats:sub>1<\/jats:sub>\n                    homodimer, which revealed that the dimer is bridged by electron transfer between two hemes. This allows electrons to move freely within and between dimers to distribute between four catalytic sites.\n                  <\/jats:p>","DOI":"10.1126\/science.1190899","type":"journal-article","created":{"date-parts":[[2010,7,22]],"date-time":"2010-07-22T14:56:28Z","timestamp":1279810588000},"page":"451-454","source":"Crossref","is-referenced-by-count":122,"title":["An Electronic Bus Bar Lies in the Core of Cytochrome bc\n                    <sub>1<\/sub>"],"prefix":"10.1126","volume":"329","author":[{"given":"Monika","family":"\u015awierczek","sequence":"first","affiliation":[{"name":"Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krak\u00f3w, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewelina","family":"Cieluch","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krak\u00f3w, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Sarewicz","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krak\u00f3w, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadiusz","family":"Borek","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krak\u00f3w, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher C.","family":"Moser","sequence":"additional","affiliation":[{"name":"The Johnson Research Foundation, Department of Biochemistry and Biophysics, University of Pennsylvania, PA 19104, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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