{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:22:48Z","timestamp":1791314568638,"version":"4.3.1"},"reference-count":39,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5997","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2010,9,10]]},"abstract":"<jats:title>Pointing the Finger<\/jats:title>\n                  <jats:p>\n                    Filopodia are finger-like structures containing parallel bundles of actin filaments that are central to eukaryotic cell motility in a variety of contexts.\n                    <jats:bold>\n                      K. Lee\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"1341\" related-article-type=\"in-this-issue\" vol=\"329\" xlink:href=\"10.1126\/science.1191710\">1341<\/jats:related-article>\n                    ) reconstituted filopodia-like structures that grow from supported lipid bilayers to explore filopodia assembly. A structural transition from actin networks to parallel bundles was observed that mediated self-assembly of filopodia-tip complexes on the membranes.\n                  <\/jats:p>","DOI":"10.1126\/science.1191710","type":"journal-article","created":{"date-parts":[[2010,9,9]],"date-time":"2010-09-09T14:05:20Z","timestamp":1284041120000},"page":"1341-1345","source":"Crossref","is-referenced-by-count":176,"title":["Self-Assembly of Filopodia-Like Structures on Supported Lipid Bilayers"],"prefix":"10.1126","volume":"329","author":[{"given":"Kwonmoo","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA."},{"name":"Department of Physics, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Gallop","sequence":"additional","affiliation":[{"name":"Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komal","family":"Rambani","sequence":"additional","affiliation":[{"name":"Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc W.","family":"Kirschner","sequence":"additional","affiliation":[{"name":"Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1175862"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/361721a0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/35009107"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(01)00506-1"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200210174"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(04)00108-4"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.09.039"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E05-11-1088"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0050317"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/34208"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1001-897"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kve197"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/cm.20312"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E07-09-0964"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200208059"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200311040"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nphys1071"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2007.09.020"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.06.027"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.95.1.223"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.146.5.1097"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200603013"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.01.011"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.211420498"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2007.03.009"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200708123"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2121-9-65"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2005.11.005"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(04)74347-7"},{"key":"e_1_3_2_31_2","doi-asserted-by":"crossref","unstructured":"P. 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