{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:15:38Z","timestamp":1792271738865,"version":"4.4.0"},"reference-count":34,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6002","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2010,10,15]]},"abstract":"Taking the Cystine<\/jats:title>\n \n Kidney stones that form from\n l<\/jats:sc>\n -cystine are much less common than those forming from calcium oxalate monohydrate, but are more likely to cause chronic kidney disease.\n \n Rimer\n et al.<\/jats:italic>\n <\/jats:bold>\n (p.\n 337<\/jats:related-article>\n ; see the cover; see the Perspective by\n \n Coe and Asplin<\/jats:related-article>\n <\/jats:bold>\n ) designed two structural mimics for\n l<\/jats:sc>\n -cystine. Atomic force microscopy showed that at low concentrations, the mimics could change the\n l<\/jats:sc>\n -cystine crystal habit and inhibit overall crystal growth. These structural mimics may thus offer hope for treating cystinuria.\n <\/jats:p>","DOI":"10.1126\/science.1191968","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T14:24:02Z","timestamp":1287066242000},"page":"337-341","source":"Crossref","is-referenced-by-count":244,"title":["Crystal Growth Inhibitors for the Prevention of\n l<\/scp>\n -Cystine Kidney Stones Through Molecular Design"],"prefix":"10.1126","volume":"330","author":[{"given":"Jeffrey D.","family":"Rimer","sequence":"first","affiliation":[{"name":"Department of Chemistry and the Molecular Design Institute, New York University (NYU), 100 Washington Square East, New York, NY 10003\u20136688, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihua","family":"An","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the Molecular Design Institute, New York University (NYU), 100 Washington Square East, New York, NY 10003\u20136688, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zina","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the Molecular Design Institute, New York University (NYU), 100 Washington Square East, New York, NY 10003\u20136688, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the Molecular Design Institute, New York University (NYU), 100 Washington Square East, New York, NY 10003\u20136688, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Goldfarb","sequence":"additional","affiliation":[{"name":"Nephrology Section, New York Harbor Veterans Affairs Medical Center, and School of Medicine, NYU, New York, NY 10010, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Wesson","sequence":"additional","affiliation":[{"name":"Nephrology Division, Department of Veterans Affairs Medical Center and the Medical College of Wisconsin, 5000 West National Avenue, Milwaukee, WI 53295, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Chemistry and the Molecular Design Institute, New York University (NYU), 100 Washington Square East, New York, NY 10003\u20136688, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2005.044156"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2005.19.429"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2008.01.011"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68071-9"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2006.00722.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67011-5"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.263.5151.1261"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr000020j"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp990641k"},{"key":"e_1_3_2_12_2","first-page":"617","volume":"6","author":"Girija E. 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