{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:41:34Z","timestamp":1791297694621,"version":"4.1.0"},"reference-count":33,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6016","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2011,1,28]]},"abstract":"<jats:p>An oncogenic fusion protein promotes lymphomagenesis by activating a noncanonical signaling pathway.<\/jats:p>","DOI":"10.1126\/science.1198946","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T14:49:21Z","timestamp":1296139761000},"page":"468-472","source":"Crossref","is-referenced-by-count":154,"title":["Cleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF-\u03baB Activation"],"prefix":"10.1126","volume":"331","author":[{"given":"Shaun","family":"Rosebeck","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Madden","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufang","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid J.","family":"Apel","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Appert","sequence":"additional","affiliation":[{"name":"Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Laboratory Block, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rifat A.","family":"Hamoudi","sequence":"additional","affiliation":[{"name":"Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Laboratory Block, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Noels","sequence":"additional","affiliation":[{"name":"Human Genome Laboratory, Molecular Genetics, Center for Human Genetics, Catholic University Leuven, B-3000 Leuven, Belgium."},{"name":"Human Genome Laboratory, Department of Molecular and Developmental Genetics, Flanders Institute for Biotechnology (VIB), B-3000 Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Sagaert","sequence":"additional","affiliation":[{"name":"Section of Morphology and Molecular Pathology, Department of Pathology, Catholic University Leuven, B-3000 Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Van Loo","sequence":"additional","affiliation":[{"name":"Human Genome Laboratory, Molecular Genetics, Center for Human Genetics, Catholic University Leuven, B-3000 Leuven, Belgium."},{"name":"Human Genome Laboratory, Department of Molecular and Developmental Genetics, Flanders Institute for Biotechnology (VIB), B-3000 Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathijs","family":"Baens","sequence":"additional","affiliation":[{"name":"Human Genome Laboratory, Molecular Genetics, Center for Human Genetics, Catholic University Leuven, B-3000 Leuven, Belgium."},{"name":"Human Genome Laboratory, Department of Molecular and Developmental Genetics, Flanders Institute for Biotechnology (VIB), B-3000 Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Qing","family":"Du","sequence":"additional","affiliation":[{"name":"Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Laboratory Block, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.","family":"Lucas","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda M.","family":"McAllister-Lucas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI, 48109, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1409"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2338"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009984200"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(04)00236-9"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1210342"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2005.04.012"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209954"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/385540a0"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9792"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2007.08.029"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.10.030"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.10.037"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni1561"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni1568"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611038200"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-10-3236"},{"key":"e_1_3_2_20_2","first-page":"961","article-title":"Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma","volume":"6","author":"Uren A. G.","year":"2000","unstructured":"Uren A. G., et al.., Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol. Cell 6, 961 (2000).11090634","journal-title":"Mol. Cell"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni0308-231"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M403286200"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1678"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1676"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2007.07.004"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600391"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-083808"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.07.010"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-02-075143"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-077222"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1042\/BST0380217"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1203652"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20041185"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2237183100"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0805186105"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-4590"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1198946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T09:48:38Z","timestamp":1704880118000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1198946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,28]]},"references-count":33,"journal-issue":{"issue":"6016","published-print":{"date-parts":[[2011,1,28]]}},"alternative-id":["10.1126\/science.1198946"],"URL":"https:\/\/doi.org\/10.1126\/science.1198946","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.8193956.8610054","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.8193956.8608055","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,28]]}}}