{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:09:26Z","timestamp":1791263366050,"version":"4.1.0"},"reference-count":37,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6102","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2012,9,28]]},"abstract":"<jats:title>A Tight Squeeze<\/jats:title>\n                  <jats:p>\n                    During intracellular transport, the export of procollagen from the endoplasmic reticulum is intriguing because procollagen is too large to fit into conventional coat protein complex II (COPII)\u2013coated transport vesicles. Recent work has implicated the receptor TANGO1 in procollagen export. Now,\n                    <jats:bold>\n                      Venditti\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"1668\" related-article-type=\"in-this-issue\" vol=\"337\" xlink:href=\"10.1126\/science.1224947\">1668<\/jats:related-article>\n                    ) report that TANGO1 recruits Sedlin\u2014also known as TRAPPC2, a homolog of the yeast TRAPP subunit Trs20\u2014and helps to allow COPII-coated carriers to grow large enough to incorporate procollagen.\n                  <\/jats:p>","DOI":"10.1126\/science.1224947","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T13:49:15Z","timestamp":1349012955000},"page":"1668-1672","source":"Crossref","is-referenced-by-count":169,"title":["Sedlin Controls the ER Export of Procollagen by Regulating the Sar1 Cycle"],"prefix":"10.1126","volume":"337","author":[{"given":"Rossella","family":"Venditti","sequence":"first","affiliation":[{"name":"Telethon Institute of Genetics and Medicine, Via Pietro Castellino 111, Naples 80131, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Scanu","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Santoro","sequence":"additional","affiliation":[{"name":"Telethon Institute of Genetics and Medicine, Via Pietro Castellino 111, Naples 80131, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Di Tullio","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Spaar","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Gaibisso","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galina V.","family":"Beznoussenko","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander A.","family":"Mironov","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Alexander","family":"Mironov","sequence":"additional","affiliation":[{"name":"Consorzio Mario Negri Sud, Via Nazionale, Santa Maria Imbaro (Chieti) 66030, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopoldo","family":"Zelante","sequence":"additional","affiliation":[{"name":"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Foggia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rosaria","family":"Piemontese","sequence":"additional","affiliation":[{"name":"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Foggia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Notarangelo","sequence":"additional","affiliation":[{"name":"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Foggia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Cell and Developmental Biology, Centre de Regulacio Genomica, 08010 Barcelona, Spain."},{"name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats, Pg. 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