{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T11:45:49Z","timestamp":1792928749232,"version":"4.5.0"},"reference-count":38,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6098","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2012,8,31]]},"abstract":"<jats:title>Skin Specifics<\/jats:title>\n                  <jats:p>\n                    Much of the recent attention paid to the trillions of bacteria that colonize our bodies has been given to the bacteria that reside in the gut.\n                    <jats:bold>\n                      Naik\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"1115\" related-article-type=\"in-this-issue\" vol=\"337\" xlink:href=\"10.1126\/science.1225152\">1115<\/jats:related-article>\n                    , published online 26 July) report that colonization of the skin with commensal bacteria is important for tuning effector T cell responses in the skin and for protective immunity against cutaneous infection with the parasite\n                    <jats:italic>Leishmania major<\/jats:italic>\n                    in mice. In contrast, selective depletion of the gut microbiota, which plays an important role in modulating immune responses in the gut, had no impact on T cell responses in the skin.\n                  <\/jats:p>","DOI":"10.1126\/science.1225152","type":"journal-article","created":{"date-parts":[[2012,7,27]],"date-time":"2012-07-27T16:27:38Z","timestamp":1343406458000},"page":"1115-1119","source":"Crossref","is-referenced-by-count":1017,"title":["Compartmentalized Control of Skin Immunity by Resident Commensals"],"prefix":"10.1126","volume":"337","author":[{"given":"Shruti","family":"Naik","sequence":"first","affiliation":[{"name":"Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA."},{"name":"Immunology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, 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