{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T10:28:45Z","timestamp":1792578525214,"version":"4.5.0"},"reference-count":53,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6112","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2012,12,7]]},"abstract":"<jats:title>\n                    CF\n                    <jats:sub>3<\/jats:sub>\n                    from Fluoroform\n                  <\/jats:title>\n                  <jats:p>\n                    Fluoroform (CF\n                    <jats:sub>3<\/jats:sub>\n                    H) is a by-product from the manufacture of fluorocarbon-based materials used, for example, in nonstick coatings and refrigerants. Fluoroform's potency as a greenhouse gas is a growing concern as supplies continue to accumulate. In this context,\n                    <jats:bold>\n                      Prakash\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"1324\" related-article-type=\"in-this-issue\" vol=\"338\" xlink:href=\"10.1126\/science.1227859\">1324<\/jats:related-article>\n                    ; see the Perspective by\n                    <jats:bold>\n                      <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6112\" page=\"1298\" related-article-type=\"in-this-issue\" vol=\"338\" xlink:href=\"10.1126\/science.1231092\">Haufe<\/jats:related-article>\n                    <\/jats:bold>\n                    ) show that fluoroform can be used to transfer CF\n                    <jats:sub>3<\/jats:sub>\n                    to silicon, sulfur, and carbon centers in the development of CF\n                    <jats:sub>3<\/jats:sub>\n                    -bearing pharmaceutical and agrochemical structures.\n                  <\/jats:p>","DOI":"10.1126\/science.1227859","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T17:38:06Z","timestamp":1354815486000},"page":"1324-1327","source":"Crossref","is-referenced-by-count":310,"title":["Taming of Fluoroform: Direct Nucleophilic Trifluoromethylation of Si, B, S, and C Centers"],"prefix":"10.1126","volume":"338","author":[{"given":"G. 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