{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:44:57Z","timestamp":1791294297111,"version":"4.1.0"},"reference-count":20,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6141","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2013,7,5]]},"abstract":"<jats:title>Female Infertility<\/jats:title>\n                  <jats:p>\n                    Anovulation, the failure of a woman's ovary to release an oocyte, is a major cause of female infertility. The mechanisms of ovulation have been studied extensively, with the hypothalamicpituitary axis serving as a key player in its regulation.\n                    <jats:bold>\n                      Hasuwa\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6141\" page=\"71\" related-article-type=\"in-this-issue\" vol=\"341\" xlink:href=\"10.1126\/science.1237999\">71<\/jats:related-article>\n                    , published online 13 June) describe a mechanism by which anovulation can be caused by the disruption of two microRNAs that are expressed in the pituitary gland.\n                  <\/jats:p>","DOI":"10.1126\/science.1237999","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T01:40:42Z","timestamp":1371174042000},"page":"71-73","source":"Crossref","is-referenced-by-count":163,"title":["MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility"],"prefix":"10.1126","volume":"341","author":[{"given":"Hidetoshi","family":"Hasuwa","sequence":"first","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Yamadaoka 3-1, Suita, Osaka 565-0871, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ueda","sequence":"additional","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Yamadaoka 3-1, Suita, Osaka 565-0871, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahito","family":"Ikawa","sequence":"additional","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Yamadaoka 3-1, Suita, Osaka 565-0871, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Okabe","sequence":"additional","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Yamadaoka 3-1, Suita, Osaka 565-0871, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1798"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.06.017"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2010.06.001"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl1118"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(02)00809-6"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2619"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1261\/rna.2146903"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81073-9"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.4.694"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0638"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5279.1219"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504270102"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.14.9.5692"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.122.10.3319"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1722"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1640608"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(02)03680-3"},{"key":"e_1_3_2_19_2","unstructured":"E. Harlow D. Lane Eds Antibodies: A Laboratory Manual. 2nd ed. (Cold Spring Harbor Laboratory Press Cold Spring Harbor New York ed. 2 1988)."},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2009.09.004"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.K09E-186"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1237999","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T09:35:28Z","timestamp":1704879328000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1237999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,5]]},"references-count":20,"journal-issue":{"issue":"6141","published-print":{"date-parts":[[2013,7,5]]}},"alternative-id":["10.1126\/science.1237999"],"URL":"https:\/\/doi.org\/10.1126\/science.1237999","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718070396.793481915","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,5]]}}}