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Working in mice,\n                    <jats:bold>\n                      Corder\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6152\" page=\"1394\" related-article-type=\"in-this-issue\" vol=\"341\" xlink:href=\"10.1126\/science.1239403\">1394<\/jats:related-article>\n                    ) observed the prolonged constitutive activation of \u00b5-opioid receptors in the spinal dorsal horn after transient peripheral inflammation. The results suggest that constitutive activation of \u00b5-opioid receptors depresses nociception\u2014the perception of pain\u2014for long periods of time and induces cellular and physical dependence on endogenous opioid signaling.\n                  <\/jats:p>","DOI":"10.1126\/science.1239403","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T15:22:00Z","timestamp":1379604120000},"page":"1394-1399","source":"Crossref","is-referenced-by-count":236,"title":["Constitutive \u03bc-Opioid Receptor Activity Leads to Long-Term Endogenous Analgesia and Dependence"],"prefix":"10.1126","volume":"341","author":[{"given":"G.","family":"Corder","sequence":"first","affiliation":[{"name":"Department of Physiology, University of Kentucky, Lexington, KY 40536, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Doolen","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Kentucky, Lexington, KY 40536, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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