{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:13:58Z","timestamp":1793834038114,"version":"4.6.1"},"reference-count":39,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6153","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2013,9,27]]},"abstract":"Diurnal Immunology<\/jats:title>\n \n Like most organ systems in the body, several components of the immune system appear to be regulated in a diurnal manner. However, the cell populations affected, the underlying molecular mechanisms controlling these processes, and the functional consequences of such regulation are poorly understood. Now,\n \n Nguyen\n et al.<\/jats:italic>\n <\/jats:bold>\n (p.\n 1483<\/jats:related-article>\n , published online 22 August; see the Perspective by\n \n Druzd and Scheiermann<\/jats:bold>\n <\/jats:related-article>\n ) have found that trafficking of monocytes to sites of inflammation is regulated in a diurnal manner in mice. Mice harboring a myeloid cell-specific deletion in the clock protein, BMAL1, showed reduced fitness in response to both acute and chronic inflammation.\n <\/jats:p>","DOI":"10.1126\/science.1240636","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T01:09:08Z","timestamp":1377220148000},"page":"1483-1488","source":"Crossref","is-referenced-by-count":660,"title":["Circadian Gene\n Bmal1<\/i>\n Regulates Diurnal Oscillations of Ly6C\n hi<\/sup>\n Inflammatory Monocytes"],"prefix":"10.1126","volume":"341","author":[{"given":"Khoa D.","family":"Nguyen","sequence":"first","affiliation":[{"name":"Cardiovascular Research Institute, University of California, San Francisco, CA 94158\u20139001, USA."},{"name":"Immunology Program, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Fentress","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, 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