{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:47:51Z","timestamp":1791298071065,"version":"4.1.0"},"reference-count":27,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6159","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2013,11,8]]},"abstract":"<jats:title>Mitochondrial Fusion and Heart Development<\/jats:title>\n                  <jats:p>\n                    The role of mitochondria in fueling homeostatic cell processes is well appreciated, but whether and how they influence cell differentiation is much less clear. Using in vivo embryonic mouse models and mouse embryonic stem cell cultures,\n                    <jats:bold>\n                      Kasahara\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6159\" page=\"734\" related-article-type=\"in-this-issue\" vol=\"342\" xlink:href=\"10.1126\/science.1241359\">734<\/jats:related-article>\n                    , published online 3 October) found that an intact mitochondrial fusion pathway was essential for the cellular signaling that drives mesodermal cell differentiation into cardiomyocytes.\n                  <\/jats:p>","DOI":"10.1126\/science.1241359","type":"journal-article","created":{"date-parts":[[2013,10,3]],"date-time":"2013-10-03T23:24:42Z","timestamp":1380842682000},"page":"734-737","source":"Crossref","is-referenced-by-count":350,"title":["Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling"],"prefix":"10.1126","volume":"342","author":[{"given":"Atsuko","family":"Kasahara","sequence":"first","affiliation":[{"name":"Department of Cell Physiology and Metabolism, University of Geneva, 1206 Geneva, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Cipolat","sequence":"additional","affiliation":[{"name":"Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, 35129 Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Center for Pharmacogenomics, Washington University School of Medicine, St. Louis, MO, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"II","given":"Gerald W.","family":"Dorn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Center for Pharmacogenomics, Washington University School of Medicine, St. Louis, MO, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scorrano","sequence":"additional","affiliation":[{"name":"Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, 35129 Padova, Italy."},{"name":"Department of Biology, University of Padua, 35121 Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099320"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/stem.590"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio0766"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm005"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.026"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.236745"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.258723"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1231031"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0955-0674(95)80071-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1383706"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000226497.52052.2a"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/19083"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/386855a0"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201000102"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.137.3.633"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808249105"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81573-1"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.5.1825-1835.2000"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.01.015"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201110058"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2012.04.054"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-0520fje"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/gene.10022"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.217513"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.233528"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl005"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.06.025"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1241359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T09:31:46Z","timestamp":1704879106000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1241359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,8]]},"references-count":27,"journal-issue":{"issue":"6159","published-print":{"date-parts":[[2013,11,8]]}},"alternative-id":["10.1126\/science.1241359"],"URL":"https:\/\/doi.org\/10.1126\/science.1241359","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718131798.793486845","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718131798.793487166","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,8]]}}}