{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:16:01Z","timestamp":1791616561583,"version":"4.3.4"},"reference-count":29,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6171","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2014,2,7]]},"abstract":"<jats:title>The Switch That Doesn't<\/jats:title>\n                  <jats:p>\n                    In mammals, a class of neurons in the brain normally switches from excitatory to inhibitory functions at birth.\n                    <jats:bold>\n                      Tyzio\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6171\" page=\"675\" related-article-type=\"in-this-issue\" vol=\"343\" xlink:href=\"10.1126\/science.1247190\">675<\/jats:related-article>\n                    ; see the Perspective by\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6171\" page=\"620\" related-article-type=\"in-this-issue\" vol=\"343\" xlink:href=\"10.1126\/science.1250214\">\n                      <jats:bold>Zimmerman and Connors<\/jats:bold>\n                    <\/jats:related-article>\n                    ) studied how these neurons function in rat and mouse models of autism. The results show that oxytocin normally accelerates the switch in function, but in these two animal models, the switch fails. The dysfunction could be replicated in normal animals using an oxytocin receptor antagonist.\n                  <\/jats:p>","DOI":"10.1126\/science.1247190","type":"journal-article","created":{"date-parts":[[2014,2,6]],"date-time":"2014-02-06T14:20:12Z","timestamp":1391696412000},"page":"675-679","source":"Crossref","is-referenced-by-count":584,"title":["Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring"],"prefix":"10.1126","volume":"343","author":[{"given":"Roman","family":"Tyzio","sequence":"first","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Nardou","sequence":"additional","affiliation":[{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana C.","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timur","family":"Tsintsadze","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."},{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amene","family":"Shahrokhi","sequence":"additional","affiliation":[{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaz","family":"Eftekhari","sequence":"additional","affiliation":[{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilgam","family":"Khalilov","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Tsintsadze","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Brouchoud","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevieve","family":"Chazal","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lemonnier","sequence":"additional","affiliation":[{"name":"Laboratoire de Neurosciences de Brest EA4685, Brest, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Lozovaya","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nail","family":"Burnashev","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehezkel","family":"Ben-Ari","sequence":"additional","affiliation":[{"name":"Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France."},{"name":"UMR 901, Aix-Marseille University, Marseille, France."},{"name":"Neurochlore, Campus scientific de Luminy, 163 route de Luminy, Marseille 13273, Cedex 09, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2011.10.010"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-183X.2003.00037.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11689-009-9023-x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.21252"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/16697"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1133212"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2011.00003"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr041"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6265-11.2012"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2007.01.002"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3193"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-011-1431-6"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197708000-00007"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3373"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1440-11.2011"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2107"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/aur.228"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.61.6.618"},{"key":"e_1_3_2_22_2","first-page":"355","article-title":"Paradoxical reactions elicited by diazepam in children with classic autism","volume":"2","author":"Marrosu F.","year":"1987","unstructured":"Marrosu F., Marrosu G., Rachel M. G., Biggio G., Paradoxical reactions elicited by diazepam in children with classic autism. Funct. Neurol. 2, 355\u2013361 (1987).2826308","journal-title":"Funct. Neurol."},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12330"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.03.005"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.124"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/2040-2392-3-16"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.09.002"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1071111"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300518"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2005.08.019"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003067"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.1247190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T10:42:07Z","timestamp":1704883327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.1247190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,7]]},"references-count":29,"journal-issue":{"issue":"6171","published-print":{"date-parts":[[2014,2,7]]}},"alternative-id":["10.1126\/science.1247190"],"URL":"https:\/\/doi.org\/10.1126\/science.1247190","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718269031.793490632","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718269031.793495276","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718269031.793491918","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,7]]}}}