{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:11:48Z","timestamp":1791353508073,"version":"4.3.1"},"reference-count":33,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6192","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2014,7,4]]},"abstract":"<jats:title>Exploiting nervous paths already traveled<\/jats:title>\n                  <jats:p>\n                    The parasympathetic nervous system helps regulate the functions of many tissues and organs, including the salivary glands and the esophagus. To do so, it needs to reach throughout the body, connecting central systems to peripheral ones. Dyachuk\n                    <jats:italic>et al.<\/jats:italic>\n                    and Espinosa-Medina\n                    <jats:italic>et al.<\/jats:italic>\n                    explored how these connections are established in mice (see the Perspective by Kalcheim and Rohrer). Progenitor cells that travel along with the developing nerves can give rise to both myelinforming Schwann cells and to parasympathetic neurons. That means the interacting nerves do not have to find each other. Instead, the beginnings of the connections are laid down as the nervous system develops.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6192\" page=\"82\" related-article-type=\"in-this-issue\" vol=\"345\" xlink:href=\"10.1126\/science.1253281\">82<\/jats:related-article>\n                    , p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6192\" page=\"87\" related-article-type=\"in-this-issue\" vol=\"345\" xlink:href=\"10.1126\/science.1253286\">87<\/jats:related-article>\n                    ; see also p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6192\" page=\"32\" related-article-type=\"in-this-issue\" vol=\"345\" xlink:href=\"10.1126\/science.1257175\">32<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.1253286","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T03:43:13Z","timestamp":1402630993000},"page":"87-90","source":"Crossref","is-referenced-by-count":204,"title":["Parasympathetic ganglia derive from Schwann cell precursors"],"prefix":"10.1126","volume":"345","author":[{"given":"I.","family":"Espinosa-Medina","sequence":"first","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Outin","sequence":"additional","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. A.","family":"Picard","sequence":"additional","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Chettouh","sequence":"additional","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Dymecki","sequence":"additional","affiliation":[{"name":"Department of Genetics, Harvard Medical School, Boston, MA 02115, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. G.","family":"Consalez","sequence":"additional","affiliation":[{"name":"Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Coppola","sequence":"additional","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-F.","family":"Brunet","sequence":"additional","affiliation":[{"name":"Institut de Biologie de l\u2019\u00c9cole Normale Sup\u00e9rieure, Inserm U1024, and CNRS UMR 8197, 75005 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","unstructured":"E. Kandel J. Schwartz T. Jessell S. Siegelbaum A. J. Hudspeth Principles of Neural Science Fifth Edition (McGraw Hill New York 2012)."},{"key":"e_1_3_2_3_2","unstructured":"W. W. 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