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Pretreatment with drugs that either potentiated or attenuated the morphine rotation indicated involvement of the noradrenergic and cholinergic systems and excluded a role for the dopaminergic system. No analgesia was observed after morphine microinjection in this site; thus, the hyperresponsivity to mild auditory and visual stimuli and concurrent analgesia previously seen in animals with morphine microinjections in the periaqueductal gray matter appear to be dissociable effects of morphine, and site specific.<\/jats:p>","DOI":"10.1126\/science.1257766","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T15:51:28Z","timestamp":1160063488000},"page":"261-263","source":"Crossref","is-referenced-by-count":28,"title":["Morphine-Induced Rotation in Naive, Nonlesioned Rats"],"prefix":"10.1126","volume":"192","author":[{"given":"Yasuko F.","family":"Jacquet","sequence":"first","affiliation":[{"name":"New York State Research Institute for Neurochemistry and Drug Addiction, Ward's Island 10035"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilyn","family":"Carol","sequence":"additional","affiliation":[{"name":"New York State Research Institute for Neurochemistry and Drug Addiction, Ward's Island 10035"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian S.","family":"Russell","sequence":"additional","affiliation":[{"name":"Medical Research Council, Unit on Neural Mechanism of Behaviour, University College, London University, London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","unstructured":"COOLS A.R. 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