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Mutations in a region called the K13-propeller are predictive for artemisinin resistance in Southeast Asia. Mok\n et al.<\/jats:italic>\n looked at the patterns of gene expression in parasites isolated from more than 1000 patients sampled in Africa, Bangladesh, and the Mekong region. A range of mutations that alter protein repair pathways and the timing of the parasite's developmental cycle were only found in parasites from the Mekong region. Straimer\n et al.<\/jats:italic>\n genetically engineered the K13 region of parasites obtained from recent clinical isolates. 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