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Yet what smoking does to our genetic material is still not fully understood. New work suggests that men should be particularly concerned. In a study of over 6000 men, Dumanski\n            <jats:italic>et al.<\/jats:italic>\n            find that men who smoke are more than three times as likely as nonsmokers to show loss of the Y chromosome in their blood cells. Whether this is a causal factor in cancer development or simply a marker of more consequential damage on other chromosomes could not be deduced from the study.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Science<\/jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6217\" page=\"81\" related-article-type=\"in-this-issue\" vol=\"347\" xlink:href=\"10.1126\/science.1262092\">81<\/jats:related-article>\n          <\/jats:p>","DOI":"10.1126\/science.1262092","type":"journal-article","created":{"date-parts":[[2014,12,5]],"date-time":"2014-12-05T05:21:37Z","timestamp":1417756897000},"page":"81-83","source":"Crossref","is-referenced-by-count":243,"title":["Smoking is associated with mosaic loss of chromosome Y"],"prefix":"10.1126","volume":"347","author":[{"given":"Jan P.","family":"Dumanski","sequence":"first","affiliation":[{"name":"Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden."},{"name":"Science for Life Laboratory, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Rasi","sequence":"additional","affiliation":[{"name":"Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden."},{"name":"Science for Life Laboratory, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"L\u00f6nn","sequence":"additional","affiliation":[{"name":"S\u00f6dert\u00f6rn University, School of Life Sciences, Biology, Huddinge, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden."},{"name":"Science for Life Laboratory, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Ingelsson","sequence":"additional","affiliation":[{"name":"Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vilmantas","family":"Giedraitis","sequence":"additional","affiliation":[{"name":"Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Lannfelt","sequence":"additional","affiliation":[{"name":"Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik K. 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