{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T23:09:17Z","timestamp":1770505757931,"version":"3.49.0"},"reference-count":5,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3445","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1961,1,6]]},"abstract":"<jats:p>In the rat, chronic treatment with isoproterenol can cause a selective growth of the salivary glands to approximately five times their normal size within 17 days. This enlargement is principally due to mitotic proliferation and hypertrophy of the parenchymatous cells.<\/jats:p>","DOI":"10.1126\/science.133.3445.44","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T08:12:02Z","timestamp":1160035922000},"page":"44-45","source":"Crossref","is-referenced-by-count":258,"title":["Excessive Stimulation of Salivary Gland Growth by Isoproterenol"],"prefix":"10.1126","volume":"133","author":[{"given":"Hans","family":"Selye","sequence":"first","affiliation":[{"name":"Institut de M\u00e9decine et de Chirurgie exp\u00e9rimentales, Universit\u00e9 de Montr\u00e9al, Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Veilleux","sequence":"additional","affiliation":[{"name":"Institut de M\u00e9decine et de Chirurgie exp\u00e9rimentales, Universit\u00e9 de Montr\u00e9al, Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Cantin","sequence":"additional","affiliation":[{"name":"Institut de M\u00e9decine et de Chirurgie exp\u00e9rimentales, Universit\u00e9 de Montr\u00e9al, Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"273","volume":"2","year":"1960","unstructured":"Selye, H., Cor et Vasa 2: 273 (1960).","journal-title":"Cor et Vasa"},{"key":"e_1_2_1_2_1","first-page":"997","volume":"101","year":"1959","unstructured":"Kley, W., Munch. med. Wochschr. 101: 997 (1959).","journal-title":"Munch. med. Wochschr."},{"key":"e_1_2_1_3_1","first-page":"771","volume":"86","year":"1956","unstructured":"Rauch, S., Schweiz. med. Wochschr. 86: 771 (1956).","journal-title":"Schweiz. med. Wochschr."},{"key":"e_1_2_1_4_1","unstructured":"Braude-Heller F. Am. JOINT Distribution Comm. (1946)."},{"key":"e_1_2_1_5_1","first-page":"11","volume":"5","year":"1951","unstructured":"Flusser, J., Sbornik, pathofysiol. traveni vyzivy 5: 11 (1951).","journal-title":"Sbornik, pathofysiol. traveni vyzivy"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.133.3445.44","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T21:11:09Z","timestamp":1704921069000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.133.3445.44"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1961,1,6]]},"references-count":5,"journal-issue":{"issue":"3445","published-print":{"date-parts":[[1961,1,6]]}},"alternative-id":["10.1126\/science.133.3445.44"],"URL":"https:\/\/doi.org\/10.1126\/science.133.3445.44","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1961,1,6]]}}}