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The chimeric protein consisted of the amino-terminal transactivation domain of E2A linked to the carboxyl-terminal basic region-leucine zipper domain of HLF. HLF was normally expressed in liver and kidney, but not in lymphoid cells, and was found to be closely related to the leucine zipper-containing transcription factors DBP (albumin D-box binding protein) and TEF (thyrotroph embryonic factor), which regulate developmental stage-specific gene expression.\n          <\/jats:p>","DOI":"10.1126\/science.1386162","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T23:03:06Z","timestamp":1160089386000},"page":"531-534","source":"Crossref","is-referenced-by-count":242,"title":["Fusion of the Leucine Zipper Gene\n            <i>HLF<\/i>\n            to the\n            <i>E2A<\/i>\n            Gene in Human Acute B-Lineage Leukemia"],"prefix":"10.1126","volume":"257","author":[{"given":"Toshiya","family":"Inaba","sequence":"first","affiliation":[{"name":"Departments of Hematology- Oncology, Tumor Cell Biology, and Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, and the Departments of Pediatrics and Pathology, University of Tennessee College of Medicine, Memphis, TN 38163."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Mark","family":"Roberts","sequence":"additional","affiliation":[{"name":"Departments of Hematology- Oncology, Tumor Cell Biology, and Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, and the Departments of Pediatrics and Pathology, University of Tennessee College of Medicine, Memphis, TN 38163."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda H.","family":"Shapiro","sequence":"additional","affiliation":[{"name":"Departments of Hematology- Oncology, Tumor Cell Biology, and Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, and the Departments of Pediatrics and Pathology, University of Tennessee College of Medicine, Memphis, TN 38163."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent W.","family":"Jolly","sequence":"additional","affiliation":[{"name":"Departments of Hematology- Oncology, Tumor Cell Biology, and Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, and the Departments of Pediatrics and Pathology, University of Tennessee College of Medicine, Memphis, TN 38163."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana C.","family":"Raimondi","sequence":"additional","affiliation":[{"name":"Departments of Hematology- Oncology, Tumor Cell Biology, and Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, and the Departments of Pediatrics and Pathology, University of Tennessee College of Medicine, Memphis, TN 38163."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen D.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Chicago, Chicago, IL 60637"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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