{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T02:51:16Z","timestamp":1776826276442,"version":"3.51.2"},"reference-count":13,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3621","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1964,5,22]]},"abstract":"<jats:p>The relationship between smoking and pulmonary emphysema was explored in 71 autopsies, by correlating Gough-Wentworth lung macrosections with smoking histories. An increasing percentage of smokers was found with each increment of emphysema. Particularly close relationship was observed between centrilobular emphysema and smoking. No definite association was found between smoking and panlobular emphysema.<\/jats:p>","DOI":"10.1126\/science.144.3621.1025","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T09:47:29Z","timestamp":1160041649000},"page":"1025-1026","source":"Crossref","is-referenced-by-count":38,"title":["Emphysema in Lung Macrosections Correlated with Smoking Habits"],"prefix":"10.1126","volume":"144","author":[{"suffix":"Jr.","given":"Augustus E.","family":"Anderson","sequence":"first","affiliation":[{"name":"Research Laboratory, Baptist Memorial Hospital, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Research Laboratory, Baptist Memorial Hospital, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillippa","family":"Eckert","sequence":"additional","affiliation":[{"name":"Research Laboratory, Baptist Memorial Hospital, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvan G.","family":"Foraker","sequence":"additional","affiliation":[{"name":"Research Laboratory, Baptist Memorial Hospital, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","unstructured":"Advisory Committee to the Surgeon General of the Public Health Service Smoking and Health (1964)."},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1056\/NEJM196210182671601","volume":"267","year":"1962","unstructured":"ANDERSON, D.O., ROLE OF TOBACCO SMOKING IN CAUSATION OF CHRONIC RESPIRATORY DISEASE, NEW ENGLAND JOURNAL OF MEDICINE 267: 787 (1962).","journal-title":"NEW ENGLAND JOURNAL OF MEDICINE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1056\/NEJM196108102650601","volume":"265","year":"1961","unstructured":"AUERBACH, O, CHANGES IN BRONCHIAL EPITHELIUM IN RELATION TO CIGARETTE SMOKING AND IN RELATION TO LUNG CANCER, NEW ENGLAND JOURNAL OF MEDICINE 265: 253 (1961).","journal-title":"NEW ENGLAND JOURNAL OF MEDICINE"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1056\/NEJM196311142692001","volume":"269","year":"1963","unstructured":"AUERBACH, O, SMOKING HABITS AND AGE IN RELATION TO PULMONARY CHANGES - RUPTURE OF ALVEOLAR SEPTUMS, FIBROSIS AND THICKENING OF WALLS OF SMALL ARTERIES AND ARTERIOLES, NEW ENGLAND JOURNAL OF MEDICINE 269: 1045 (1963).","journal-title":"NEW ENGLAND JOURNAL OF MEDICINE"},{"key":"e_1_2_1_5_1","first-page":"684","volume":"87","year":"1963","unstructured":"BRINKMAN, G.L., EFFECT OF BRONCHITIS, SMOKING, AND OCCUPATION ON VENTILATION, AMERICAN REVIEW OF RESPIRATORY DISEASE 87: 684 (1963).","journal-title":"AMERICAN REVIEW OF RESPIRATORY DISEASE"},{"key":"e_1_2_1_6_1","first-page":"483","volume":"80","year":"1959","unstructured":"FLETCHER, C.M., CHRONIC BRONCHITIS - ITS PREVALENCE, NATURE, AND PATHOGENESIS, AMERICAN REVIEW OF RESPIRATORY DISEASE 80: 483 (1959).","journal-title":"AMERICAN REVIEW OF RESPIRATORY DISEASE"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1001\/archinte.1959.00270100004002","volume":"104","year":"1959","unstructured":"FLICK, A.L., OBSTRUCTIVE EMPHYSEMA IN CIGARETTE SMOKERS, ARCHIVES OF INTERNAL MEDICINE 104: 518 (1959).","journal-title":"ARCHIVES OF INTERNAL MEDICINE"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.7326\/0003-4819-54-3-379","volume":"54","year":"1961","unstructured":"FRANKLIN, W, UNRECOGNIZED AIRWAY OBSTRUCTION ASSOCIATED WITH SMOKING - A PROBABLE FORERUNNER OF OBSTRUCTIVE PULMONARY EMPHYSEMA, ANNALS OF INTERNAL MEDICINE 54: 379 (1961).","journal-title":"ANNALS OF INTERNAL MEDICINE"},{"key":"e_1_2_1_9_1","first-page":"80","year":"1960","unstructured":"Gough, J., Recent Advances in Pathology: 80 (1960).","journal-title":"Recent Advances in Pathology"},{"key":"e_1_2_1_10_1","first-page":"82","volume":"77","year":"1964","unstructured":"HERNANDEZ, J.A., BRONCHIAL CHARACTERISTICS IN PULMONARY EMPHYSEMA, ARCHIVES OF PATHOLOGY 77: 82 (1964).","journal-title":"ARCHIVES OF PATHOLOGY"},{"key":"e_1_2_1_11_1","first-page":"630","volume":"88","year":"1963","unstructured":"LARSEN, R.K., CHRONIC EFFECT OF CIGARETTE SMOKING ON PULMONARY VENTILATION, AMERICAN REVIEW OF RESPIRATORY DISEASE 88: 630 (1963).","journal-title":"AMERICAN REVIEW OF RESPIRATORY DISEASE"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1136\/thx.12.3.219","volume":"12","year":"1957","unstructured":"Leopold, J., Thorax 12: 219 (1957).","journal-title":"Thorax"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1136\/thx.18.1.59","volume":"18","year":"1963","unstructured":"Thurlbeck, W. M., Thorax 18: 59 (1963).","journal-title":"Thorax"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.144.3621.1025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T03:15:52Z","timestamp":1704942952000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.144.3621.1025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,5,22]]},"references-count":13,"journal-issue":{"issue":"3621","published-print":{"date-parts":[[1964,5,22]]}},"alternative-id":["10.1126\/science.144.3621.1025"],"URL":"https:\/\/doi.org\/10.1126\/science.144.3621.1025","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1964,5,22]]}}}