{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:57:57Z","timestamp":1770739077611,"version":"3.49.0"},"reference-count":27,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5070","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1992,7,31]]},"abstract":"<jats:p>\n            Although nonclassical (class I-b) gene products represent the majority of murine major histocompatibility complex (MHC) genes, the role of these relatively nonpolymorphic molecules remains uncertain. Recently, one such protein, H-2M3 (formerly designated Hmt), was shown to bind and specifically present\n            <jats:italic>N<\/jats:italic>\n            -formylated peptides to cytotoxic T lymphocytes. Because\n            <jats:italic>N<\/jats:italic>\n            -formylation is characteristic of prokaryotic proteins, this MHC molecule may be especially adapted for a role in the mammalian defense against bacterial attack. The current studies demonstrate that an MHC molecule, indistinguishable from H-2M3, presents antigens derived from the intracellular pathogen\n            <jats:italic>Listeria monocytogenes<\/jats:italic>\n            to\n            <jats:italic>Listeria<\/jats:italic>\n            -specific CD8\n            <jats:sup>+<\/jats:sup>\n            cells.\n          <\/jats:p>","DOI":"10.1126\/science.1496381","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T23:03:06Z","timestamp":1160089386000},"page":"678-679","source":"Crossref","is-referenced-by-count":95,"title":["Specialized Role for a Murine Class I-b MHC Molecule in Prokaryotic Host Defenses"],"prefix":"10.1126","volume":"257","author":[{"given":"Roger J.","family":"Kurlander","sequence":"first","affiliation":[{"name":"Department of Medicine, Duke Medical Center, Durham, NC 27710."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said M.","family":"Shawar","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology and the Department of Medicine, Baylor College of Medicine, Houston, TX 77030."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda L.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke Medical Center, Durham, NC 27710."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert R.","family":"Rich","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology and the Department of Medicine, Baylor College of Medicine, Houston, TX 77030."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.4049\/jimmunol.148.2.555","volume":"148","year":"1992","unstructured":"BROWN, M.L., METABOLIC REQUIREMENTS FOR MACROPHAGE PRESENTATION OF LISTERIA-MONOCYTOGENES TO IMMUNE CD8 CELLS, JOURNAL OF IMMUNOLOGY 148: 555 (1992).","journal-title":"JOURNAL OF IMMUNOLOGY"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.4049\/jimmunol.145.11.3540","volume":"145","year":"1990","unstructured":"BRUNT, L.M., PRESENTATION OF LISTERIA-MONOCYTOGENES TO CD8+ T-CELLS REQUIRES SECRETION OF HEMOLYSIN AND INTRACELLULAR BACTERIAL-GROWTH, JOURNAL OF IMMUNOLOGY 145: 3540 (1990).","journal-title":"JOURNAL OF IMMUNOLOGY"},{"key":"e_1_2_1_3_1","first-page":"1","volume":"5","year":"1978","unstructured":"BUETOW, D, SUBCELL BIOCH 5: 1 (1978).","journal-title":"SUBCELL BIOCH"},{"key":"e_1_2_1_4_1","first-page":"287","volume":"60","year":"1987","unstructured":"CZUPRYNSKI, C.J., DUAL REGULATION OF ANTIBACTERIAL RESISTANCE AND INFLAMMATORY NEUTROPHIL AND MACROPHAGE ACCUMULATION BY L3T4+ AND LYT2+ LISTERIA-IMMUNE T-CELLS, IMMUNOLOGY 60: 287 (1987).","journal-title":"IMMUNOLOGY"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/eji.1830180102","volume":"18","year":"1988","unstructured":"DELIBERO, G, EUR J IMMUNOL 18: 1 (1988).","journal-title":"EUR J IMMUNOL"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.4049\/jimmunol.137.8.2688","volume":"137","year":"1986","unstructured":"DELIBERO, G, ANTIGEN-SPECIFIC LYT-2+ CYTOLYTIC LYMPHOCYTES-T FROM MICE INFECTED WITH THE INTRACELLULAR BACTERIUM LISTERIA-MONOCYTOGENES, JOURNAL OF IMMUNOLOGY 137: 2688 (1986).","journal-title":"JOURNAL OF IMMUNOLOGY"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1146\/annurev.iy.09.040191.002031","volume":"9","year":"1991","unstructured":"FISCHERLINDAHL, K, ANNU REV IMMUNOL 9: 351 (1991).","journal-title":"ANNU REV IMMUNOL"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0168-9525(85)90055-1","volume":"1","year":"1985","unstructured":"FISCHERLINDAHL, K, TRENDS GENET 1: 135 (1985).","journal-title":"TRENDS GENET"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/306383a0","volume":"306","year":"1983","unstructured":"FISCHERLINDAHL, K, NATURE 306: 383 (1983).","journal-title":"NATURE"},{"key":"e_1_2_1_10_1","first-page":"10475","volume":"88","year":"1991","unstructured":"IMANI, F, HEAT-SHOCK PROTEINS CAN REGULATE EXPRESSION OF THE TLA REGION-ENCODED CLASS-IB MOLECULE QA-1, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88: 10475 (1991).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.4049\/jimmunol.140.9.3173","volume":"140","year":"1988","unstructured":"KAUFMANN, SHE, CLONED LISTERIA-MONOCYTOGENES SPECIFIC NON-MHC-RESTRICTED LYT-2+ T-CELLS WITH CYTOLYTIC AND PROTECTIVE ACTIVITY, JOURNAL OF IMMUNOLOGY 140: 3173 (1988).","journal-title":"JOURNAL OF IMMUNOLOGY"},{"key":"e_1_2_1_12_1","first-page":"5650","volume":"9","year":"1987","unstructured":"KAUFMANN, S. 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