{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:22:38Z","timestamp":1784193758150,"version":"3.55.0"},"reference-count":10,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3694","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1965,10,15]]},"abstract":"<jats:p>A passage line of a spontaneous hamster fibrosarcoma is contaminated by the virus of lymphocytic choriomeningitis. Tumors from animals receiving implants when newborn contain high titers of infectious lymphocytic-choriomeningitis virus and complement-fixing antigen, and hamsters receiving implants when weanlings develop high titers of complement-fixing antibody against lymphocytic-choriomeningitis virus. In contrast with the specific reactions of tumorous hamsters to the initiating virus in virus-induced tumors, the development of complement-fixing antibody to lymphocytic-choriomeningitis virus does not depend on the development of tumors. Infant hamsters bearing the tumor have a generalized subclinical infection and seem able to spread virus to other hamsters and to humans.<\/jats:p>","DOI":"10.1126\/science.150.3694.363","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T10:04:55Z","timestamp":1160042695000},"page":"363-364","source":"Crossref","is-referenced-by-count":38,"title":["Lymphocytic-Choriomeningitis Virus in Hamster Tumor: Spread to Hamsters and Humans"],"prefix":"10.1126","volume":"150","author":[{"suffix":"Jr.","given":"Andrew M.","family":"Lewis","sequence":"first","affiliation":[{"name":"National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wallace P.","family":"Rowe","sequence":"additional","affiliation":[{"name":"National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horace C.","family":"Turner","sequence":"additional","affiliation":[{"name":"National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Huebner","sequence":"additional","affiliation":[{"name":"National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"1148","volume":"50","year":"1963","unstructured":"BLACK, P.H., A SPECIFIC COMPLEMENT-FIXING ANTIGEN PRESENT IN SV40 TUMOR AND TRANSFORMED CELLS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50: 1148 (1963).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_2_1","first-page":"161","volume":"21","year":"1961","unstructured":"FORTNER, J. 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