{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:25:13Z","timestamp":1767374713509},"reference-count":11,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3766","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1967,3,3]]},"abstract":"<jats:p>\n            In a series of\n            <jats:italic>Xenopus<\/jats:italic>\n            larvae (stages 28 to 35), the left eye cup was dorsoventrally and anteroposteriorly inverted. After metamorphosis, the retinotectal projection was mapped by recording action potentials evoked in the tectum by a small spot of light projected on the retina. Normal retinotectal projection was found following rotation of the eye cup at stage 28 to 29. Rotation of the eye cup at stage 30 resulted in anteroposterior inversion of the retinotectal projection; rotation at stages 31, 32, and 35 resulted in inversion of the projection in anteroposterior and dorsoventral axis of the retina. Therefore the retinal ganglion cells were unspecified at stage 28 to 29; spatial specification of ganglion cells occurred in the anteroposterior axis of the eye cup at stage 30 and in the dorsoventral axis between stages 30 and 31.\n          <\/jats:p>","DOI":"10.1126\/science.155.3766.1106","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T11:08:12Z","timestamp":1160046492000},"page":"1106-1108","source":"Crossref","is-referenced-by-count":42,"title":["Retinal Ganglion Cells: Specification of Central Connections in Larval\n            <i>Xenopus laevis<\/i>"],"prefix":"10.1126","volume":"155","author":[{"given":"Marcus","family":"Jacobson","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Purdue University, Lafayette, Indiana 47907"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1113\/jphysiol.1963.sp007072","volume":"165","year":"1963","unstructured":"GAZE, R.M., J PHYSIOL-LONDON 165: 484 (1963).","journal-title":"J PHYSIOL-LONDON"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1113\/expphysiol.1959.sp001402","volume":"44","year":"1959","unstructured":"GAZE, R.M., QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY 44: 290 (1959).","journal-title":"QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02474628","volume":"2","year":"1964","unstructured":"GULD, C, MED ELECTRON BIOL EN 2: 317 (1964).","journal-title":"MED ELECTRON BIOL EN"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1113\/expphysiol.1962.sp001588","volume":"47","year":"1962","unstructured":"JACOBSON, M, REPRESENTATION OF RETINA ON OPTIC TECTUM OF FROG - CORRELATION BETWEEN RETINOTECTAL MAGNIFICATION FACTOR AND RETINAL GANGLION CELL COUNT, QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES 47: 170 (1962).","journal-title":"QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES"},{"key":"e_1_2_1_5_1","unstructured":"Nieuwkoop P. 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Normal Table of Xenopus laevis (Daudin) (1956)."},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1749-6632.1948.tb30968.x","volume":"49","year":"1948","unstructured":"STONE, L.S., FUNCTIONAL POLARIZATION IN DEVELOPING AND REGENERATING RETINAE OF TRANSPLANTED EYES, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 49: 856 (1948).","journal-title":"ANNALS OF THE NEW YORK ACADEMY OF SCIENCES"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/jez.1401450108","volume":"145","year":"1960","unstructured":"STON, L.S., POLARIZATION OF THE RETINA AND DEVELOPMENT OF VISION, JOURNAL OF EXPERIMENTAL ZOOLOGY 145: 85 (1960).","journal-title":"JOURNAL OF EXPERIMENTAL ZOOLOGY"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3181\/00379727-57-14678P","volume":"57","year":"1944","unstructured":"STONE, L.S., Functional polarization in retinal development and its reestablishment in regenerating retinae of rotated grafted eyes, PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 57: 13 (1944).","journal-title":"PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE"},{"key":"e_1_2_1_9_1","first-page":"157","volume":"5","year":"1954","unstructured":"SZEKELY, G, ACTA BIOLOGICA HUNGARICA 5: 157 (1954).","journal-title":"ACTA BIOLOGICA HUNGARICA"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/BF00574906","volume":"150","year":"1957","unstructured":"SZEKELY, G, ARCH ENTW ORG 150: 48 (1957).","journal-title":"ARCH ENTW ORG"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.132.3436.1309"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.155.3766.1106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T09:41:03Z","timestamp":1704966063000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.155.3766.1106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1967,3,3]]},"references-count":11,"journal-issue":{"issue":"3766","published-print":{"date-parts":[[1967,3,3]]}},"alternative-id":["10.1126\/science.155.3766.1106"],"URL":"https:\/\/doi.org\/10.1126\/science.155.3766.1106","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1967,3,3]]}}}