{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T20:26:23Z","timestamp":1789676783246,"version":"4.0.1"},"reference-count":10,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3803","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1967,11,17]]},"abstract":"<jats:p>\n            Acid extracts of thyroid glands from a small shark\n            <jats:italic>Squalus suckleyi<\/jats:italic>\n            and domestic fowl\n            <jats:italic>Gallus domestica<\/jats:italic>\n            contained no detectable calcitonin activity, while very potent hypocalcemic responses were obtained in rats with similar extracts from the ultimobranchial glands of these two species. The calcitonin concentration was 4 to 40 times that present in hog thyroid, which, as in most other mammals, contains ultimobranchial tissue. The evidence suggests that calcitonin is a fundamental calcium-regulating hormone present in all higher vertebrates and that it is an ultimobranchial rather than a thyroid hormone. It also indicates an important and hitherto unrecognized function for the ultimobranchial glands.\n          <\/jats:p>","DOI":"10.1126\/science.158.3803.924","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T11:08:12Z","timestamp":1160046492000},"page":"924-925","source":"Crossref","is-referenced-by-count":126,"title":["Calcitonin from Ultimobranchial Glands of Dogfish and Chickens"],"prefix":"10.1126","volume":"158","author":[{"given":"D. H.","family":"Copp","sequence":"first","affiliation":[{"name":"Department of Physiology, University of British Columbia, Vancouver 8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. W.","family":"Cockcroft","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of British Columbia, Vancouver 8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yankoon","family":"Kueh","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of British Columbia, Vancouver 8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1677\/joe.0.0370205","volume":"37","year":"1967","unstructured":"BUSSOLATI, G, IMMUNOFLUORESCENT LOCALIZATION OF CALCITONIN IN C CELLS OF PIG AND DOG THYROID, JOURNAL OF ENDOCRINOLOGY 37: 205 (1967).","journal-title":"JOURNAL OF ENDOCRINOLOGY"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/jmor.1050280203","volume":"28","year":"1917","unstructured":"CAMP, W. 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