{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:45:03Z","timestamp":1767707103687},"reference-count":2,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3867","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1969,2,7]]},"abstract":"<jats:p>Weanling, germfree rats, transferred to a conventional animal room and fed a vitamin A-deficient diet, died in 23 to 54 days. In contrast, their littermates, kept germfree and on the same diet, survived for as long as 272 days. The rats kept in germfree conditions stopped growing after 1 to 4 months but responded to supplements of retinoic acid.<\/jats:p>","DOI":"10.1126\/science.163.3867.574","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T12:14:21Z","timestamp":1160050461000},"page":"574-575","source":"Crossref","is-referenced-by-count":40,"title":["Survival of Germfree Rats without Vitamin A"],"prefix":"10.1126","volume":"163","author":[{"given":"J. G.","family":"Bieri","sequence":"first","affiliation":[{"name":"Laboratory of Nutrition and Endocrinology, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland 20014"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. G.","family":"McDaniel","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition and Endocrinology, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland 20014"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"W. E.","family":"Rogers","sequence":"additional","affiliation":[{"name":"Laboratory of Nutrition and Endocrinology, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland 20014"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"335","volume":"38","year":"1961","unstructured":"BEAVER, D.L., VITAMIN A DEFICIENCY IN GERM-FREE RAT, AMERICAN JOURNAL OF PATHOLOGY 38: 335 (1961).","journal-title":"AMERICAN JOURNAL OF PATHOLOGY"},{"key":"e_1_2_1_2_1","unstructured":"RAICA N PERSONAL COMMUNICATION."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.163.3867.574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T10:37:06Z","timestamp":1704969426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.163.3867.574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,2,7]]},"references-count":2,"journal-issue":{"issue":"3867","published-print":{"date-parts":[[1969,2,7]]}},"alternative-id":["10.1126\/science.163.3867.574"],"URL":"https:\/\/doi.org\/10.1126\/science.163.3867.574","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,2,7]]}}}