{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:31:26Z","timestamp":1760981486640},"reference-count":5,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3872","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1969,3,14]]},"abstract":"<jats:p>An image analysis computer has been used to count and measure goblet cells in the epithelium of the bronchiolar tree of rats exposed to sulfur dioxide vapor. A technique was developed which enabled a bioassay of the irritant effects of the gas.<\/jats:p>","DOI":"10.1126\/science.163.3872.1200","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T12:14:21Z","timestamp":1160050461000},"page":"1200-1200","source":"Crossref","is-referenced-by-count":20,"title":["Automated Analysis of Cellular Change in Histological Sections"],"prefix":"10.1126","volume":"163","author":[{"given":"Lionel E.","family":"Mawdesley-Thomas","sequence":"first","affiliation":[{"name":"Department of Pathology, Huntingdon Research Centre, Huntingdon, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Healey","sequence":"additional","affiliation":[{"name":"Department of Pathology, Huntingdon Research Centre, Huntingdon, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"148","volume":"15","year":"1966","unstructured":"COLE, M, MICROSCOPE & CRYSTAL FRONT 15: 148 (1966).","journal-title":"MICROSCOPE & CRYSTAL FRONT"},{"key":"e_1_2_1_2_1","first-page":"77","year":"1967","unstructured":"Fisher, C., Proceedings of the Particle Size Analysis Conference: 77 (1967).","journal-title":"Proceedings of the Particle Size Analysis Conference"},{"key":"e_1_2_1_3_1","first-page":"437","volume":"44","year":"1963","unstructured":"REID, L, AN EXPERIMENTAL STUDY OF HYPERSECRETION OF MUCUS IN BRONCHIAL TREE, BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY 44: 437 (1963).","journal-title":"BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY"},{"key":"e_1_2_1_4_1","first-page":"235","article-title":"Chronic bronchitis and hypersecretion of mucus","volume":"8","year":"1959","unstructured":"REID, L, Chronic bronchitis and hypersecretion of mucus, LECTURES ON THE SCIENTIFIC BASIS OF MEDICINE 8: 235 (1959).","journal-title":"LECTURES ON THE SCIENTIFIC BASIS OF MEDICINE"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1136\/thx.15.2.132","volume":"15","year":"1960","unstructured":"REID, L, THORAX 15: 132 (1960).","journal-title":"THORAX"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.163.3872.1200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T15:01:08Z","timestamp":1704985268000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.163.3872.1200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,3,14]]},"references-count":5,"journal-issue":{"issue":"3872","published-print":{"date-parts":[[1969,3,14]]}},"alternative-id":["10.1126\/science.163.3872.1200"],"URL":"https:\/\/doi.org\/10.1126\/science.163.3872.1200","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,3,14]]}}}