{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:59:29Z","timestamp":1775923169206,"version":"3.50.1"},"reference-count":5,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"3902","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1969,10,10]]},"abstract":"<jats:p>\n            <jats:italic>Frullania<\/jats:italic>\n            spp. (Hepaticae, Jungermanniales) are agents of allergies. Extraction and fractionation of\n            <jats:italic>Frullania tamarisci<\/jats:italic>\n            has given, as the only allergenic component isolated, a levorotatory crystalline substance, the structure of which is demonstrated. It is a sesquiterpene lactone. The racemic (\u00b1) form is isolated from a mixed sample of\n            <jats:italic>Frullania tamarisci<\/jats:italic>\n            and\n            <jats:italic>Frullania dilatata<\/jats:italic>\n            ; the dextrorotatory form, from\n            <jats:italic>Frullania dilatata<\/jats:italic>\n            . The observed allergenic properties are shared by some other sesquiterpene lactones.\n          <\/jats:p>","DOI":"10.1126\/science.166.3902.239","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T12:14:21Z","timestamp":1160050461000},"page":"239-240","source":"Crossref","is-referenced-by-count":77,"title":["Allergenic Component of a Liverwort: A Sesquiterpene Lactone"],"prefix":"10.1126","volume":"166","author":[{"given":"H.","family":"Knoche","sequence":"first","affiliation":[{"name":"Laboratoire Associ\u00e9 au CNRS, Institut de Chimie, 67-Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Ourisson","sequence":"additional","affiliation":[{"name":"Laboratoire Associ\u00e9 au CNRS, Institut de Chimie, 67-Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. W.","family":"Perold","sequence":"additional","affiliation":[{"name":"Laboratoire Associ\u00e9 au CNRS, Institut de Chimie, 67-Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Foussereau","sequence":"additional","affiliation":[{"name":"Clinique Dermatologique, H\u00f4pital Civil, 67-Strasbourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Maleville","sequence":"additional","affiliation":[{"name":"Clinique Dermatologique, H\u00f4pital Civil, 67-Strasbourg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"463","volume":"3","year":"1964","unstructured":"Hegnauer, R., Chemotaxonomie der Pflanzen 3: 463 (1964).","journal-title":"Chemotaxonomie der Pflanzen"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0031-9422(00)86295-0","volume":"6","year":"1967","unstructured":"HUNECK, S, INHALTSSTOFFE DER MOOSE .3. UBER DIE VERGLEICHENDE GAS- UND DUNNSCHICHT-CHROMATOGRAPHISCHE UNTERSUCHUNG DER ATHERISCHEN OLE EINIGER LEBERMOOSE UND DIE ISOLIERUNG VON (-)-LONGIFOLEN UND (-)-LONGIBORNEOL AUS SCAPANIA UNDULATA (L) DUM, PHYTOCHEMISTRY 6: 383 (1967).","journal-title":"PHYTOCHEMISTRY"},{"key":"e_1_2_1_3_1","first-page":"440","volume":"73","year":"1966","unstructured":"LECOULANT, BULLETIN DE LA SOCIETE FRANCAISE DE DERMATOLOGIE ET DE SYPHILIGRAPHIE 73: 440 (1966).","journal-title":"BULLETIN DE LA SOCIETE FRANCAISE DE DERMATOLOGIE ET DE SYPHILIGRAPHIE"},{"key":"e_1_2_1_4_1","first-page":"246","volume":"133","year":"1956","unstructured":"LECOULANT, P, JOURNAL DE MEDECINE DE BORDEAUX ET DU SUD-OUEST 133: 246 (1956).","journal-title":"JOURNAL DE MEDECINE DE BORDEAUX ET DU SUD-OUEST"},{"key":"e_1_2_1_5_1","unstructured":"Ourisson G. Donnees relatives aux Sesquiterpenoides (1966)."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.166.3902.239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T16:24:09Z","timestamp":1704990249000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.166.3902.239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,10,10]]},"references-count":5,"journal-issue":{"issue":"3902","published-print":{"date-parts":[[1969,10,10]]}},"alternative-id":["10.1126\/science.166.3902.239"],"URL":"https:\/\/doi.org\/10.1126\/science.166.3902.239","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,10,10]]}}}